Sheehan VA - Search Results

1

Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells.

Zhang Y, Paikari A, Sumazin P, Ginter Summarell CC, Crosby JR, Boerwinkle E, Weiss MJ, Sheehan VA. Zhang Y, et al. Among authors: sheehan va. Blood. 2018 Jul 19;132(3):321-333. doi: 10.1182/blood-2017-11-814335. Epub 2018 Jun 8. Blood. 2018. PMID: 29884740 Free PMC article.

2

Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.

Flanagan JM, Sheehan V, Linder H, Howard TA, Wang YD, Hoppe CC, Aygun B, Adams RJ, Neale GA, Ware RE. Flanagan JM, et al. Blood. 2013 Apr 18;121(16):3237-45. doi: 10.1182/blood-2012-10-464156. Epub 2013 Feb 19. Blood. 2013. PMID: 23422753 Free PMC article. Clinical Trial.

3

Transcranial Doppler velocity and brain MRI/MRA changes in children with sickle cell anemia on chronic transfusions to prevent primary stroke.

Sheehan VA, Hansbury EN, Smeltzer MP, Fortner G, McCarville MB, Aygun B. Sheehan VA, et al. Pediatr Blood Cancer. 2013 Sep;60(9):1499-502. doi: 10.1002/pbc.24569. Epub 2013 Apr 26. Pediatr Blood Cancer. 2013. PMID: 23625812 Clinical Trial.

4

Whole exome sequencing identifies novel genes for fetal hemoglobin response to hydroxyurea in children with sickle cell anemia.

Sheehan VA, Crosby JR, Sabo A, Mortier NA, Howard TA, Muzny DM, Dugan-Perez S, Aygun B, Nottage KA, Boerwinkle E, Gibbs RA, Ware RE, Flanagan JM. Sheehan VA, et al. PLoS One. 2014 Oct 31;9(10):e110740. doi: 10.1371/journal.pone.0110740. eCollection 2014. PLoS One. 2014. PMID: 25360671 Free PMC article. Clinical Trial.

5

The role of BCL11A and HMIP-2 polymorphisms on endogenous and hydroxyurea induced levels of fetal hemoglobin in sickle cell anemia patients from southern Brazil.

Friedrisch JR, Sheehan V, Flanagan JM, Baldan A, Summarell CC, Bittar CM, Friedrisch BK, Wilke II, Ribeiro CB, Daudt LE, da Rocha Silla LM. Friedrisch JR, et al. Blood Cells Mol Dis. 2016 Nov;62:32-37. doi: 10.1016/j.bcmd.2016.11.002. Epub 2016 Nov 9. Blood Cells Mol Dis. 2016. PMID: 27838552 Free PMC article.

6

p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy.

Moreno-Smith M, Lakoma A, Chen Z, Tao L, Scorsone KA, Schild L, Aviles-Padilla K, Nikzad R, Zhang Y, Chakraborty R, Molenaar JJ, Vasudevan SA, Sheehan V, Kim ES, Paust S, Shohet JM, Barbieri E. Moreno-Smith M, et al. Clin Cancer Res. 2017 Nov 1;23(21):6629-6639. doi: 10.1158/1078-0432.CCR-17-0668. Epub 2017 Aug 18. Clin Cancer Res. 2017. PMID: 28821555 Free PMC article.

7

Fetal haemoglobin induction in sickle cell disease.

Paikari A, Sheehan VA. Paikari A, et al. Among authors: sheehan va. Br J Haematol. 2018 Jan;180(2):189-200. doi: 10.1111/bjh.15021. Epub 2017 Nov 16. Br J Haematol. 2018. PMID: 29143315 Free PMC article. Review.

8

Genetic modifiers of severity in sickle cell disease.

Chang AK, Ginter Summarell CC, Birdie PT, Sheehan VA. Chang AK, et al. Among authors: sheehan va. Clin Hemorheol Microcirc. 2018;68(2-3):147-164. doi: 10.3233/CH-189004. Clin Hemorheol Microcirc. 2018. PMID: 29614629

9

Echocardiography Differentiates Lethally Irradiated Whole-Body From Partial-Body Exposed Rats.

Inoue T, Zawaski JA, Sheehan V, Kanne C, Paikari A, Kaffes CC, Sarkar P, Sabek OM, Gaber MW. Inoue T, et al. Front Cardiovasc Med. 2018 Oct 16;5:138. doi: 10.3389/fcvm.2018.00138. eCollection 2018. Front Cardiovasc Med. 2018. PMID: 30460240 Free PMC article.

10

Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease.

Park SH, Lee CM, Dever DP, Davis TH, Camarena J, Srifa W, Zhang Y, Paikari A, Chang AK, Porteus MH, Sheehan VA, Bao G. Park SH, et al. Among authors: sheehan va. Nucleic Acids Res. 2019 Sep 5;47(15):7955-7972. doi: 10.1093/nar/gkz475. Nucleic Acids Res. 2019. PMID: 31147717 Free PMC article.

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