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Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.
Singanayagam A, Glanville N, Girkin JL, Ching YM, Marcellini A, Porter JD, Toussaint M, Walton RP, Finney LJ, Aniscenko J, Zhu J, Trujillo-Torralbo MB, Calderazzo MA, Grainge C, Loo SL, Veerati PC, Pathinayake PS, Nichol KS, Reid AT, James PL, Solari R, Wark PAB, Knight DA, Moffatt MF, Cookson WO, Edwards MR, Mallia P, Bartlett NW, Johnston SL. Singanayagam A, et al. Among authors: knight da. Nat Commun. 2018 Jun 8;9(1):2229. doi: 10.1038/s41467-018-04574-1. Nat Commun. 2018. PMID: 29884817 Free PMC article.
IL-25 blockade augments antiviral immunity during respiratory virus infection.
Williams TC, Loo SL, Nichol KS, Reid AT, Veerati PC, Esneau C, Wark PAB, Grainge CL, Knight DA, Vincent T, Jackson CL, Alton K, Shimkets RA, Girkin JL, Bartlett NW. Williams TC, et al. Among authors: knight da. Commun Biol. 2022 May 4;5(1):415. doi: 10.1038/s42003-022-03367-z. Commun Biol. 2022. PMID: 35508632 Free PMC article.
Conditionally reprogrammed asthmatic bronchial epithelial cells express lower FOXJ1 at terminal differentiation and lower IFNs following RV-A1 infection.
Veerati PC, Nichol KS, Read JM, Bartlett NW, Wark PAB, Knight DA, Grainge CL, Reid AT. Veerati PC, et al. Among authors: knight da. Am J Physiol Lung Cell Mol Physiol. 2022 Oct 1;323(4):L495-L502. doi: 10.1152/ajplung.00230.2022. Epub 2022 Aug 30. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 36041223 Free PMC article.
264 results