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Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer.
Zhou G, Noordam L, Sprengers D, Doukas M, Boor PPC, van Beek AA, Erkens R, Mancham S, Grünhagen D, Menon AG, Lange JF, Burger PJWA, Brandt A, Galjart B, Verhoef C, Kwekkeboom J, Bruno MJ. Zhou G, et al. Among authors: noordam l. Oncoimmunology. 2018 Apr 25;7(7):e1448332. doi: 10.1080/2162402X.2018.1448332. eCollection 2018. Oncoimmunology. 2018. PMID: 29900067 Free PMC article.
GITR ligation enhances functionality of tumor-infiltrating T cells in hepatocellular carcinoma.
van Beek AA, Zhou G, Doukas M, Boor PPC, Noordam L, Mancham S, Campos Carrascosa L, van der Heide-Mulder M, Polak WG, Ijzermans JNM, Pan Q, Heirman C, Mahne A, Bucktrout SL, Bruno MJ, Sprengers D, Kwekkeboom J. van Beek AA, et al. Among authors: noordam l. Int J Cancer. 2019 Aug 15;145(4):1111-1124. doi: 10.1002/ijc.32181. Epub 2019 Feb 27. Int J Cancer. 2019. PMID: 30719701 Free PMC article.
Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules.
Zhou G, Sprengers D, Mancham S, Erkens R, Boor PPC, van Beek AA, Doukas M, Noordam L, Campos Carrascosa L, de Ruiter V, van Leeuwen RWF, Polak WG, de Jonge J, Groot Koerkamp B, van Rosmalen B, van Gulik TM, Verheij J, IJzermans JNM, Bruno MJ, Kwekkeboom J. Zhou G, et al. Among authors: noordam l. J Hepatol. 2019 Oct;71(4):753-762. doi: 10.1016/j.jhep.2019.05.026. Epub 2019 Jun 11. J Hepatol. 2019. PMID: 31195061
FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells.
Campos Carrascosa L, van Beek AA, de Ruiter V, Doukas M, Wei J, Fisher TS, Ching K, Yang W, van Loon K, Boor PPC, Rakké YS, Noordam L, Doornebosch P, Grünhagen D, Verhoef K, Polak WG, IJzermans JNM, Ni I, Yeung YA, Salek-Ardakani S, Sprengers D, Kwekkeboom J. Campos Carrascosa L, et al. Among authors: noordam l. J Immunother Cancer. 2020 Sep;8(2):e000816. doi: 10.1136/jitc-2020-000816. J Immunother Cancer. 2020. PMID: 32900860 Free PMC article.
TIGIT and PD1 Co-blockade Restores ex vivo Functions of Human Tumor-Infiltrating CD8+ T Cells in Hepatocellular Carcinoma.
Ge Z, Zhou G, Campos Carrascosa L, Gausvik E, Boor PPC, Noordam L, Doukas M, Polak WG, Terkivatan T, Pan Q, Takkenberg RB, Verheij J, Erdmann JI, IJzermans JNM, Peppelenbosch MP, Kraan J, Kwekkeboom J, Sprengers D. Ge Z, et al. Among authors: noordam l. Cell Mol Gastroenterol Hepatol. 2021;12(2):443-464. doi: 10.1016/j.jcmgh.2021.03.003. Epub 2021 Mar 27. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33781741 Free PMC article.
LGR5 marks targetable tumor-initiating cells in mouse liver cancer.
Cao W, Li M, Liu J, Zhang S, Noordam L, Verstegen MMA, Wang L, Ma B, Li S, Wang W, Bolkestein M, Doukas M, Chen K, Ma Z, Bruno M, Sprengers D, Kwekkeboom J, van der Laan LJW, Smits R, Peppelenbosch MP, Pan Q. Cao W, et al. Among authors: noordam l. Nat Commun. 2020 Apr 23;11(1):1961. doi: 10.1038/s41467-020-15846-0. Nat Commun. 2020. PMID: 32327656 Free PMC article.
Cancer-Associated Fibroblasts Provide a Stromal Niche for Liver Cancer Organoids That Confers Trophic Effects and Therapy Resistance.
Liu J, Li P, Wang L, Li M, Ge Z, Noordam L, Lieshout R, Verstegen MMA, Ma B, Su J, Yang Q, Zhang R, Zhou G, Carrascosa LC, Sprengers D, IJzermans JNM, Smits R, Kwekkeboom J, van der Laan LJW, Peppelenbosch MP, Pan Q, Cao W. Liu J, et al. Among authors: noordam l. Cell Mol Gastroenterol Hepatol. 2021;11(2):407-431. doi: 10.1016/j.jcmgh.2020.09.003. Epub 2020 Sep 12. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32932015 Free PMC article.
56 results