Zhang ZY - Search Results

1

Pharmacokinetics, Safety, and Tolerability of Rolapitant Administered Intravenously Following Single Ascending and Multiple Ascending Doses in Healthy Subjects.

Wang X, Zhang ZY, Wang J, Powers D, Arora S, Lu S, Kansra V. Wang X, et al. Among authors: zhang zy. Clin Pharmacol Drug Dev. 2019 Feb;8(2):160-171. doi: 10.1002/cpdd.580. Epub 2018 Jun 15. Clin Pharmacol Drug Dev. 2019. PMID: 29905976 Clinical Trial.

2

Development and validation of a liquid chromatography-tandem mass spectrometry assay for the simultaneous quantitation of prednisolone and dipyridamole in human plasma and its application in a pharmacokinetic study.

Chen M, Granvil C, Ji QC, Zhang ZY, Padval MV, Kansra VV. Chen M, et al. Among authors: zhang zy. J Pharm Biomed Anal. 2009 Jul 12;49(5):1241-9. doi: 10.1016/j.jpba.2009.02.017. Epub 2009 Feb 25. J Pharm Biomed Anal. 2009. PMID: 19304431

3

Biotransformation and in vitro assessment of metabolism-associated drug-drug interaction for CRx-102, a novel combination drug candidate.

Zhang ZY, Chen M, Chen J, Padval MV, Kansra VV. Zhang ZY, et al. J Pharm Biomed Anal. 2009 Sep 8;50(2):200-9. doi: 10.1016/j.jpba.2009.04.013. Epub 2009 Apr 19. J Pharm Biomed Anal. 2009. PMID: 19467820

4

Effects of Rolapitant Administered Intravenously or Orally on the Pharmacokinetics of Digoxin (P-glycoprotein Substrate) and Sulfasalazine (Breast Cancer Resistance Protein Substrate) in Healthy Volunteers.

Wang X, Zhang ZY, Arora S, Hughes L, Wang J, Powers D, Christensen J, Lu S, Kansra V. Wang X, et al. Among authors: zhang zy. J Clin Pharmacol. 2018 Feb;58(2):202-211. doi: 10.1002/jcph.1005. Epub 2017 Sep 14. J Clin Pharmacol. 2018. PMID: 28906558 Clinical Trial.

5

Bioequivalence of Intravenous and Oral Rolapitant: Results From a Randomized, Open-Label Pivotal Study.

Wang X, Zhang ZY, Powers D, Wang J, Lu S, Arora S, Hughes L, Christensen J, Kansra V. Wang X, et al. Among authors: zhang zy. J Clin Pharmacol. 2017 Dec;57(12):1600-1606. doi: 10.1002/jcph.966. Epub 2017 Sep 14. J Clin Pharmacol. 2017. PMID: 28906561 Clinical Trial.

6

The effect of food on the pharmacokinetics of niraparib, a poly(ADP-ribose) polymerase (PARP) inhibitor, in patients with recurrent ovarian cancer.

Moore K, Zhang ZY, Agarwal S, Burris H, Patel MR, Kansra V. Moore K, et al. Among authors: zhang zy. Cancer Chemother Pharmacol. 2018 Mar;81(3):497-503. doi: 10.1007/s00280-017-3512-5. Epub 2018 Jan 10. Cancer Chemother Pharmacol. 2018. PMID: 29322231

7

Pharmacokinetics of Rolapitant in Patients With Mild to Moderate Hepatic Impairment.

Wang J, Wang X, Zhang ZY, Arora S, Lu S, Kansra V. Wang J, et al. Among authors: zhang zy. J Clin Pharmacol. 2018 May;58(5):686-693. doi: 10.1002/jcph.1066. Epub 2018 Jan 12. J Clin Pharmacol. 2018. PMID: 29329482 Clinical Trial.

8

Effects of Rolapitant Administered Intravenously on the Pharmacokinetics of a Modified Cooperstown Cocktail (Midazolam, Omeprazole, Warfarin, Caffeine, and Dextromethorphan) in Healthy Subjects.

Wang X, Zhang ZY, Arora S, Wang J, Lu S, Powers D, Kansra V. Wang X, et al. Among authors: zhang zy. J Clin Pharmacol. 2018 Aug;58(8):1074-1083. doi: 10.1002/jcph.1114. Epub 2018 Apr 25. J Clin Pharmacol. 2018. PMID: 29693712

9

Absorption, metabolism, and excretion of the antiemetic rolapitant, a selective neurokinin-1 receptor antagonist, in healthy male subjects.

Zhang ZY, Wang J, Kansra V, Wang X. Zhang ZY, et al. Invest New Drugs. 2019 Feb;37(1):139-146. doi: 10.1007/s10637-018-0638-1. Epub 2018 Jul 21. Invest New Drugs. 2019. PMID: 30032410 Clinical Trial.

10

Effects of rolapitant administered orally on the pharmacokinetics of dextromethorphan (CYP2D6), tolbutamide (CYP2C9), omeprazole (CYP2C19), efavirenz (CYP2B6), and repaglinide (CYP2C8) in healthy subjects.

Wang J, Zhang ZY, Lu S, Powers D, Kansra V, Wang X. Wang J, et al. Among authors: zhang zy. Support Care Cancer. 2019 Mar;27(3):819-827. doi: 10.1007/s00520-018-4331-x. Epub 2018 Aug 6. Support Care Cancer. 2019. PMID: 30084103 Free PMC article. Clinical Trial.

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