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Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells.
Kühn B, Brat C, Fettel J, Hellmuth N, Maucher IV, Bulut U, Hock KJ, Grimmer J, Manolikakes G, Rühl M, Kühn A, Zacharowski K, Matrone C, Urbschat A, Roos J, Steinhilber D, Maier TJ. Kühn B, et al. Among authors: zacharowski k. Biochem Pharmacol. 2018 Sep;155:48-60. doi: 10.1016/j.bcp.2018.06.014. Epub 2018 Jun 15. Biochem Pharmacol. 2018. PMID: 29909078
The small fibrinopeptide Bβ15-42 as renoprotective agent preserving the endothelial and vascular integrity in early ischemia reperfusion injury in the mouse kidney.
Urbschat A, Zacharowski K, Obermüller N, Rupprecht K, Penzkofer D, Jennewein C, Tran N, Scheller B, Dimmeler S, Paulus P. Urbschat A, et al. Among authors: zacharowski k. PLoS One. 2014 Jan 2;9(1):e84432. doi: 10.1371/journal.pone.0084432. eCollection 2014. PLoS One. 2014. PMID: 24392138 Free PMC article.
Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy.
Roos J, Peters M, Maucher IV, Kühn B, Fettel J, Hellmuth N, Brat C, Sommer B, Urbschat A, Piesche M, Vogel A, Proschak E, Blöcher R, Buscató E, Häfner AK, Matrone C, Werz O, Heidler J, Wittig I, Angioni C, Geisslinger G, Parnham MJ, Zacharowski K, Steinhilber D, Maier TJ. Roos J, et al. Among authors: zacharowski k. Antioxid Redox Signal. 2018 May 10;28(14):1265-1285. doi: 10.1089/ars.2017.7155. Epub 2017 Sep 8. Antioxid Redox Signal. 2018. PMID: 28699354
Systemic TLR2 Antibody Application in Renal Ischaemia and Reperfusion Injury Decreases AKT Phosphorylation and Increases Apoptosis in the Mouse Kidney.
Urbschat A, Baer P, Zacharowski K, Sprunck V, Scheller B, Raimann F, Maier TJ, Hegele A, Hofmann R, Mersmann J. Urbschat A, et al. Among authors: zacharowski k. Basic Clin Pharmacol Toxicol. 2018 Feb;122(2):223-232. doi: 10.1111/bcpt.12896. Epub 2017 Sep 19. Basic Clin Pharmacol Toxicol. 2018. PMID: 28857508 Free article.
607 results