Razler TM - Search Results

1

Adventures in Atropisomerism: Total Synthesis of a Complex Active Pharmaceutical Ingredient with Two Chirality Axes.

Beutner G, Carrasquillo R, Geng P, Hsiao Y, Huang EC, Janey J, Katipally K, Kolotuchin S, La Porte T, Lee A, Lobben P, Lora-Gonzalez F, Mack B, Mudryk B, Qiu Y, Qian X, Ramirez A, Razler TM, Rosner T, Shi Z, Simmons E, Stevens J, Wang J, Wei C, Wisniewski SR, Zhu Y. Beutner G, et al. Among authors: razler tm. Org Lett. 2018 Jul 6;20(13):3736-3740. doi: 10.1021/acs.orglett.8b01218. Epub 2018 Jun 17. Org Lett. 2018. PMID: 29909639

2

Nickel-Catalyzed Synthesis of Quinazolinediones.

Beutner GL, Hsiao Y, Razler T, Simmons EM, Wertjes W. Beutner GL, et al. Org Lett. 2017 Mar 3;19(5):1052-1055. doi: 10.1021/acs.orglett.7b00052. Epub 2017 Feb 13. Org Lett. 2017. PMID: 28253632

3

Mono-Oxidation of Bidentate Bis-phosphines in Catalyst Activation: Kinetic and Mechanistic Studies of a Pd/Xantphos-Catalyzed C-H Functionalization.

Ji Y, Plata RE, Regens CS, Hay M, Schmidt M, Razler T, Qiu Y, Geng P, Hsiao Y, Rosner T, Eastgate MD, Blackmond DG. Ji Y, et al. J Am Chem Soc. 2015 Oct 21;137(41):13272-81. doi: 10.1021/jacs.5b01913. Epub 2015 Oct 13. J Am Chem Soc. 2015. PMID: 26461028

4

A preparatively convenient ligand-free catalytic PEG 2000 Suzuki-Miyaura coupling.

Razler TM, Hsiao Y, Qian F, Fu R, Khan RK, Doubleday W. Razler TM, et al. J Org Chem. 2009 Feb 6;74(3):1381-4. doi: 10.1021/jo802277z. J Org Chem. 2009. PMID: 19178357

5

(+)-Phorboxazole A synthetic studies. A highly convergent, second generation total synthesis of (+)-phorboxazole A.

Smith AB 3rd, Razler TM, Ciavarri JP, Hirose T, Ishikawa T. Smith AB 3rd, et al. Among authors: razler tm. Org Lett. 2005 Sep 29;7(20):4399-402. doi: 10.1021/ol051584i. Org Lett. 2005. PMID: 16178543

6

A second-generation total synthesis of (+)-phorboxazole A.

Smith AB 3rd, Razler TM, Ciavarri JP, Hirose T, Ishikawa T, Meis RM. Smith AB 3rd, et al. Among authors: razler tm. J Org Chem. 2008 Feb 15;73(4):1192-200. doi: 10.1021/jo7018152. Epub 2008 Jan 24. J Org Chem. 2008. PMID: 18215058

7

Design and synthesis of a potent phorboxazole C(11-15) acetal analogue.

Smith AB 3rd, Razler TM, Meis RM, Pettit GR. Smith AB 3rd, et al. Among authors: razler tm. Org Lett. 2006 Feb 16;8(4):797-9. doi: 10.1021/ol060014v. Org Lett. 2006. PMID: 16468770

8

(+)-Phorboxazole A synthetic studies. Identification of a series of highly cytotoxic C(45-46) analogues.

Smith AB 3rd, Razler TM, Pettit GR, Chapuis JC. Smith AB 3rd, et al. Among authors: razler tm. Org Lett. 2005 Sep 29;7(20):4403-6. doi: 10.1021/ol051585a. Org Lett. 2005. PMID: 16178544

9

Degradation kinetics and mechanism of an oxadiazole derivative, design of a stable drug product for BMS-708163, a γ-secretase inhibitor drug candidate.

Hartley RF, Huang Y, Cassidy M, Razler TM, Qian F, Hussain MA. Hartley RF, et al. Among authors: razler tm. J Pharm Sci. 2012 Sep;101(9):3124-33. doi: 10.1002/jps.23050. Epub 2012 Jan 19. J Pharm Sci. 2012. PMID: 22262489

10

Synthesis and biological evaluation of phorboxazole congeners leading to the discovery and preparative-scale synthesis of (+)-chlorophorboxazole a possessing picomolar human solid tumor cell growth inhibitory activity.

Smith AB 3rd, Razler TM, Meis RM, Pettit GR. Smith AB 3rd, et al. Among authors: razler tm. J Org Chem. 2008 Feb 15;73(4):1201-8. doi: 10.1021/jo701816h. Epub 2008 Jan 24. J Org Chem. 2008. PMID: 18215059

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