Schimmel P - Search Results

1

Publisher Correction: ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase.

Vo MN, Terrey M, Lee JW, Roy B, Moresco JJ, Sun L, Fu H, Liu Q, Weber TG, Yates JR 3rd, Fredrick K, Schimmel P, Ackerman SL. Vo MN, et al. Among authors: schimmel p. Nature. 2018 Aug;560(7720):E35. doi: 10.1038/s41586-018-0271-3. Nature. 2018. PMID: 29925958

2

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

Lee JW, Beebe K, Nangle LA, Jang J, Longo-Guess CM, Cook SA, Davisson MT, Sundberg JP, Schimmel P, Ackerman SL. Lee JW, et al. Among authors: schimmel p. Nature. 2006 Sep 7;443(7107):50-5. doi: 10.1038/nature05096. Epub 2006 Aug 13. Nature. 2006. PMID: 16906134

3

Dissociating quaternary structure regulates cell-signaling functions of a secreted human tRNA synthetase.

Vo MN, Yang XL, Schimmel P. Vo MN, et al. Among authors: schimmel p. J Biol Chem. 2011 Apr 1;286(13):11563-8. doi: 10.1074/jbc.C110.213876. Epub 2011 Feb 10. J Biol Chem. 2011. PMID: 21310955 Free PMC article.

4

ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase.

Zhou H, Sun L, Yang XL, Schimmel P. Zhou H, et al. Among authors: schimmel p. Nature. 2013 Feb 7;494(7435):121-4. doi: 10.1038/nature11774. Epub 2012 Dec 23. Nature. 2013. PMID: 23263184 Free PMC article.

5

RNA function. Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration.

Ishimura R, Nagy G, Dotu I, Zhou H, Yang XL, Schimmel P, Senju S, Nishimura Y, Chuang JH, Ackerman SL. Ishimura R, et al. Among authors: schimmel p. Science. 2014 Jul 25;345(6195):455-9. doi: 10.1126/science.1249749. Science. 2014. PMID: 25061210 Free PMC article.

6

Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy.

Liu Y, Satz JS, Vo MN, Nangle LA, Schimmel P, Ackerman SL. Liu Y, et al. Among authors: schimmel p. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17570-5. doi: 10.1073/pnas.1420196111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422440 Free PMC article.

7

Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.

Sun L, Gomes AC, He W, Zhou H, Wang X, Pan DW, Schimmel P, Pan T, Yang XL. Sun L, et al. Among authors: schimmel p. J Am Chem Soc. 2016 Oct 5;138(39):12948-12955. doi: 10.1021/jacs.6b07121. Epub 2016 Sep 26. J Am Chem Soc. 2016. PMID: 27622773 Free PMC article.

8

Two crystal structures reveal design for repurposing the C-Ala domain of human AlaRS.

Sun L, Song Y, Blocquel D, Yang XL, Schimmel P. Sun L, et al. Among authors: schimmel p. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14300-14305. doi: 10.1073/pnas.1617316113. Epub 2016 Nov 28. Proc Natl Acad Sci U S A. 2016. PMID: 27911835 Free PMC article.

9

An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.

Xu X, Zhou H, Zhou Q, Hong F, Vo MN, Niu W, Wang Z, Xiong X, Nakamura K, Wakasugi K, Schimmel P, Yang XL. Xu X, et al. Among authors: schimmel p. RNA Biol. 2018;15(4-5):649-658. doi: 10.1080/15476286.2017.1377868. Epub 2017 Nov 3. RNA Biol. 2018. PMID: 28910573 Free PMC article.

10

Double mimicry evades tRNA synthetase editing by toxic vegetable-sourced non-proteinogenic amino acid.

Song Y, Zhou H, Vo MN, Shi Y, Nawaz MH, Vargas-Rodriguez O, Diedrich JK, Yates JR, Kishi S, Musier-Forsyth K, Schimmel P. Song Y, et al. Among authors: schimmel p. Nat Commun. 2017 Dec 22;8(1):2281. doi: 10.1038/s41467-017-02201-z. Nat Commun. 2017. PMID: 29273753 Free PMC article.

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