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Page 1
Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD. Desjardins A, et al. Among authors: muscat am. N Engl J Med. 2018 Jul 12;379(2):150-161. doi: 10.1056/NEJMoa1716435. Epub 2018 Jun 26. N Engl J Med. 2018. PMID: 29943666 Free PMC article. Clinical Trial.
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy.
Gromeier M, Brown MC, Zhang G, Lin X, Chen Y, Wei Z, Beaubier N, Yan H, He Y, Desjardins A, Herndon JE 2nd, Varn FS, Verhaak RG, Zhao J, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Lipp ES, Nair SK, Khasraw M, Peters KB, Randazzo D, Sampson JH, McLendon RE, Bigner DD, Ashley DM. Gromeier M, et al. Among authors: muscat am. Nat Commun. 2021 Jan 13;12(1):352. doi: 10.1038/s41467-020-20469-6. Nat Commun. 2021. PMID: 33441554 Free PMC article.
Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition.
Low JT, Chandramohan V, Bowie ML, Brown MC, Waitkus MS, Briley A, Stevenson K, Fuller R, Reitman ZJ, Muscat AM, Hariharan S, Hostettler J, Danehower S, Baker A, Khasraw M, Wong NC, Gregory S, Nair SK, Heimberger A, Gromeier M, Bigner DD, Ashley DM. Low JT, et al. Among authors: muscat am. Cancer Cell. 2022 May 9;40(5):439-440. doi: 10.1016/j.ccell.2022.04.009. Epub 2022 Apr 28. Cancer Cell. 2022. PMID: 35487217 Free article. No abstract available.
Tailored NEOadjuvant epirubicin, cyclophosphamide and Nanoparticle Albumin-Bound paclitaxel for breast cancer: The phase II NEONAB trial-Clinical outcomes and molecular determinants of response.
Murphy C, Muscat A, Ashley D, Mukaro V, West L, Liao Y, Chisanga D, Shi W, Collins I, Baron-Hay S, Patil S, Lindeman G, Khasraw M. Murphy C, et al. PLoS One. 2019 Feb 14;14(2):e0210891. doi: 10.1371/journal.pone.0210891. eCollection 2019. PLoS One. 2019. PMID: 30763338 Free PMC article. Clinical Trial.
Caspase 8 is absent or low in many ex vivo gliomas.
Ashley DM, Riffkin CD, Muscat AM, Knight MJ, Kaye AH, Novak U, Hawkins CJ. Ashley DM, et al. Among authors: muscat am. Cancer. 2005 Oct 1;104(7):1487-96. doi: 10.1002/cncr.21323. Cancer. 2005. PMID: 16080161 Free article.
16 results