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Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing.
Gerhart SV, Kellner WA, Thompson C, Pappalardi MB, Zhang XP, Montes de Oca R, Penebre E, Duncan K, Boriack-Sjodin A, Le B, Majer C, McCabe MT, Carpenter C, Johnson N, Kruger RG, Barbash O. Gerhart SV, et al. Among authors: johnson n. Sci Rep. 2018 Jun 26;8(1):9711. doi: 10.1038/s41598-018-28002-y. Sci Rep. 2018. PMID: 29946150 Free PMC article.
A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC.
Mohammad HP, Smitheman KN, Kamat CD, Soong D, Federowicz KE, Van Aller GS, Schneck JL, Carson JD, Liu Y, Butticello M, Bonnette WG, Gorman SA, Degenhardt Y, Bai Y, McCabe MT, Pappalardi MB, Kasparec J, Tian X, McNulty KC, Rouse M, McDevitt P, Ho T, Crouthamel M, Hart TK, Concha NO, McHugh CF, Miller WH, Dhanak D, Tummino PJ, Carpenter CL, Johnson NW, Hann CL, Kruger RG. Mohammad HP, et al. Among authors: johnson nw. Cancer Cell. 2015 Jul 13;28(1):57-69. doi: 10.1016/j.ccell.2015.06.002. Cancer Cell. 2015. PMID: 26175415 Free article.
Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2.
Verma SK, Tian X, LaFrance LV, Duquenne C, Suarez DP, Newlander KA, Romeril SP, Burgess JL, Grant SW, Brackley JA, Graves AP, Scherzer DA, Shu A, Thompson C, Ott HM, Aller GS, Machutta CA, Diaz E, Jiang Y, Johnson NW, Knight SD, Kruger RG, McCabe MT, Dhanak D, Tummino PJ, Creasy CL, Miller WH. Verma SK, et al. ACS Med Chem Lett. 2012 Oct 19;3(12):1091-6. doi: 10.1021/ml3003346. eCollection 2012 Dec 13. ACS Med Chem Lett. 2012. PMID: 24900432 Free PMC article.
Pyridinylimidazole inhibitors of Tie2 kinase.
Semones M, Feng Y, Johnson N, Adams JL, Winkler J, Hansbury M. Semones M, et al. Among authors: johnson n. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4756-60. doi: 10.1016/j.bmcl.2007.06.068. Epub 2007 Jun 27. Bioorg Med Chem Lett. 2007. PMID: 17618114
Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.
Poulin MB, Schneck JL, Matico RE, McDevitt PJ, Huddleston MJ, Hou W, Johnson NW, Thrall SH, Meek TD, Schramm VL. Poulin MB, et al. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1197-201. doi: 10.1073/pnas.1521036113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787850 Free PMC article.
A Student-Informed Guide for Success on the OB/GYN Clerkship.
Hopkins-Kotb N, Sylla H, Krotinger A, Pelletier A, Bartz DA, Johnson NR. Hopkins-Kotb N, et al. Among authors: johnson nr. J Med Educ Curric Dev. 2025 Jan 12;12:23821205241299584. doi: 10.1177/23821205241299584. eCollection 2025 Jan-Dec. J Med Educ Curric Dev. 2025. PMID: 39807282 Free PMC article.
Video versus Direct Laryngoscopy for Tracheal Intubation Following Cardiac Arrest: a Secondary Analysis of the DEVICE Trial.
Muhs AL, Seitz KP, Qian ET, Imhoff B, Wang L, Prekker ME, Driver BE, Trent SA, Resnick-Ault D, Schauer SG, Ginde AA, Russell DW, Gandotra S, Page DB, Gaillard JP, Smith LM, Latimer AJ, Mitchell SH, Johnson NJ, Ghamande SA, White HD, Gibbs KW, Palakshappa JA, Vonderhaar DJ, Janz DR, Whitson MR, Barnes CR, Dagan A, Moskowitz A, Krishnamoorthy V, Herbert JT, April MD, Joffe AM, Walco JP, Hughes CG, Shipley JK, Maiga AW, Lloyd BD, DeMasi SC, Self WH, Rice TW, Semler MW, Casey JD; Pragmatic Critical Care Research Group. Muhs AL, et al. Among authors: johnson nj. Chest. 2025 Jan 11:S0012-3692(25)00004-2. doi: 10.1016/j.chest.2024.12.031. Online ahead of print. Chest. 2025. PMID: 39805516
Maintenance of neuronal TDP-43 expression requires axonal lysosome transport.
Ryan VH, Lawton S, Reyes JF, Hawrot J, Frankenfield AM, Seddighi S, Ramos DM, Faghri F, Johnson NL, Zou J, Kampmann M, Replogle J, Yuan H, Johnson KR, Maric D, Hao L, Nalls MA, Ward ME. Ryan VH, et al. Among authors: johnson nl. bioRxiv [Preprint]. 2024 Oct 1:2024.09.30.615241. doi: 10.1101/2024.09.30.615241. bioRxiv. 2024. PMID: 39803527 Free PMC article. Preprint.
5,049 results