Kumagai Y - Search Results

1

Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial.

Kumagai Y, Amano H, Sasaki Y, Nakagawa C, Maeda M, Oikawa I, Furuie H. Kumagai Y, et al. Br J Clin Pharmacol. 2018 Oct;84(10):2393-2404. doi: 10.1111/bcp.13698. Epub 2018 Aug 2. Br J Clin Pharmacol. 2018. PMID: 29959787 Free PMC article. Clinical Trial.

2

A Drug-Drug Interaction Study to Evaluate the Effect of TAS-303 on CYP3A Activity in the Small Intestine and Liver.

Kumagai Y, Fujita T, Maeda M, Sasaki Y, Nagaoka M, Huang J, Takenaka T, Kawai M. Kumagai Y, et al. J Clin Pharmacol. 2020 Jun;60(6):702-710. doi: 10.1002/jcph.1583. Epub 2020 Feb 5. J Clin Pharmacol. 2020. PMID: 32026490 Free PMC article. Clinical Trial.

3

A 3-Part Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DSP-6952 in Healthy Japanese Subjects and Those With ≤3 Spontaneous Bowel Movements per Week.

Yumizaki T, Maeda M, Fujita T, Kakuyama H, Kumagai Y. Yumizaki T, et al. Among authors: kumagai y. Clin Pharmacol Drug Dev. 2020 Apr;9(3):353-365. doi: 10.1002/cpdd.731. Epub 2019 Aug 28. Clin Pharmacol Drug Dev. 2020. PMID: 31464087 Clinical Trial.

4

Safety, tolerability and pharmacokinetics of TAS-108, a novel anti-oestrogen, in healthy post-menopausal Japanese women: a phase I single oral dose study.

Kumagai Y, Fujita T, Ozaki M, Yokota S, Maeda M, Shida M, Otani Y, Yamaya H, Tsuruta H. Kumagai Y, et al. Basic Clin Pharmacol Toxicol. 2009 May;104(5):352-9. doi: 10.1111/j.1742-7843.2008.00373.x. Basic Clin Pharmacol Toxicol. 2009. PMID: 19175362 Free article. Clinical Trial.

5

Population Pharmacokinetic-Pharmacodynamic Analysis to Compare the Effect of Moxifloxacin on QT Interval Prolongation Between Healthy Korean and Japanese Subjects.

Choi HK, Jung JA, Fujita T, Amano H, Ghim JL, Lee DH, Tabata K, Song ID, Maeda M, Kumagai Y, Mendzelevski B, Shin JG. Choi HK, et al. Among authors: kumagai y. Clin Ther. 2016 Dec;38(12):2610-2621. doi: 10.1016/j.clinthera.2016.10.011. Clin Ther. 2016. PMID: 28003052 Clinical Trial.

6

In vivo kinetics of indoxyl sulfate in humans and its renal interaction with angiotensin-converting enzyme inhibitor quinapril in rats.

Fujita T, Ishihara K, Yasuda S, Nakamura T, Maeda M, Kobayashi M, Sahashi K, Ikeda Y, Kumagai Y, Majima M. Fujita T, et al. Among authors: kumagai y. J Pharmacol Exp Ther. 2012 Jun;341(3):626-33. doi: 10.1124/jpet.111.187732. Epub 2012 Mar 2. J Pharmacol Exp Ther. 2012. PMID: 22389425

7

Appraisal of ICH E14/S7B Q&As adopted in February 2022 using thorough QT/QTc study data for α4-integrin antagonist carotegrast methyl in Japanese healthy subjects.

Kambayashi R, Goto A, Izumi-Nakaseko H, Oikawa I, Ikeda N, Matsuda K, Takei Y, Matsumoto A, Kumagai Y, Sugiyama A. Kambayashi R, et al. Among authors: kumagai y. J Pharmacol Sci. 2022 Nov;150(3):191-199. doi: 10.1016/j.jphs.2022.08.007. Epub 2022 Sep 2. J Pharmacol Sci. 2022. PMID: 36184124 Free article. Clinical Trial.

8

Pharmacodynamics and pharmacokinetics of AMG 531, a thrombopoiesis-stimulating peptibody, in healthy Japanese subjects: a randomized, placebo-controlled study.

Kumagai Y, Fujita T, Ozaki M, Sahashi K, Ohkura M, Ohtsu T, Arai Y, Sonehara Y, Nichol JL. Kumagai Y, et al. J Clin Pharmacol. 2007 Dec;47(12):1489-97. doi: 10.1177/0091270007306563. Epub 2007 Oct 9. J Clin Pharmacol. 2007. PMID: 17925591 Clinical Trial.

9

Pharmacokinetics, Pharmacodynamics, and Safety of E6011, a Novel Humanized Antifractalkine (CX3CL1) Monoclonal Antibody: A Randomized, Double-Blind, Placebo-Controlled Single-Ascending-Dose Study.

Tabuchi H, Katsurabara T, Mori M, Aoyama M, Obara T, Yasuda N, Kawano T, Imai T, Ieiri I, Kumagai Y. Tabuchi H, et al. Among authors: kumagai y. J Clin Pharmacol. 2019 May;59(5):688-701. doi: 10.1002/jcph.1361. Epub 2018 Dec 21. J Clin Pharmacol. 2019. PMID: 30575978 Clinical Trial.

10

Hepatic Adaptation to Therapeutic Doses of Acetaminophen: An Exploratory Study in Healthy Individuals.

Maeda M, Tanaka R, Aso M, Sakamoto Y, Song I, Ochiai M, Saito Y, Maekawa K, Arakawa N, Ohno Y, Kumagai Y. Maeda M, et al. Among authors: kumagai y. Clin Ther. 2020 Jul;42(7):1276-1291.e1. doi: 10.1016/j.clinthera.2020.05.003. Epub 2020 Jun 30. Clin Ther. 2020. PMID: 32620339 Clinical Trial.

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