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Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells.
Carruthers RD, Ahmed SU, Ramachandran S, Strathdee K, Kurian KM, Hedley A, Gomez-Roman N, Kalna G, Neilson M, Gilmour L, Stevenson KH, Hammond EM, Chalmers AJ. Carruthers RD, et al. Among authors: hammond em. Cancer Res. 2018 Sep 1;78(17):5060-5071. doi: 10.1158/0008-5472.CAN-18-0569. Epub 2018 Jul 5. Cancer Res. 2018. PMID: 29976574 Free PMC article.
Targeting hypoxic cells through the DNA damage response.
Olcina M, Lecane PS, Hammond EM. Olcina M, et al. Among authors: hammond em. Clin Cancer Res. 2010 Dec 1;16(23):5624-9. doi: 10.1158/1078-0432.CCR-10-0286. Epub 2010 Sep 27. Clin Cancer Res. 2010. PMID: 20876254 Free PMC article. Review.
Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.
Chan N, Pires IM, Bencokova Z, Coackley C, Luoto KR, Bhogal N, Lakshman M, Gottipati P, Oliver FJ, Helleday T, Hammond EM, Bristow RG. Chan N, et al. Among authors: hammond em. Cancer Res. 2010 Oct 15;70(20):8045-54. doi: 10.1158/0008-5472.CAN-10-2352. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924112 Free PMC article.
Targeting radiation-resistant hypoxic tumour cells through ATR inhibition.
Pires IM, Olcina MM, Anbalagan S, Pollard JR, Reaper PM, Charlton PA, McKenna WG, Hammond EM. Pires IM, et al. Among authors: hammond em. Br J Cancer. 2012 Jul 10;107(2):291-9. doi: 10.1038/bjc.2012.265. Epub 2012 Jun 19. Br J Cancer. 2012. PMID: 22713662 Free PMC article.
Targeting ATR in DNA damage response and cancer therapeutics.
Fokas E, Prevo R, Hammond EM, Brunner TB, McKenna WG, Muschel RJ. Fokas E, et al. Among authors: hammond em. Cancer Treat Rev. 2014 Feb;40(1):109-17. doi: 10.1016/j.ctrv.2013.03.002. Epub 2013 Apr 11. Cancer Treat Rev. 2014. PMID: 23583268 Review.
129 results