Karcher H - Search Results

1

The "RCT augmentation": a novel simulation method to add patient heterogeneity into phase III trials.

Karcher H, Fu S, Meng J, Ankarfeldt MZ, Efthimiou O, Belger M, Haro JM, Abenhaim L, Nordon C; GetReal Consortium Work Package 2. Karcher H, et al. BMC Med Res Methodol. 2018 Jul 6;18(1):75. doi: 10.1186/s12874-018-0534-6. BMC Med Res Methodol. 2018. PMID: 29980181 Free PMC article.

2

The "Efficacy-Effectiveness Gap": Historical Background and Current Conceptualization.

Nordon C, Karcher H, Groenwold RH, Ankarfeldt MZ, Pichler F, Chevrou-Severac H, Rossignol M, Abbe A, Abenhaim L; GetReal consortium. Nordon C, et al. Among authors: karcher h. Value Health. 2016 Jan;19(1):75-81. doi: 10.1016/j.jval.2015.09.2938. Epub 2015 Nov 19. Value Health. 2016. PMID: 26797239 Free article.

3

Efficacy, Effectiveness and the "Efficacy-To-Effectiveness Gap": Review of the Current State of Play and Perspectives. First Results From the Imi Getreal Consortium.

Nordon C, Karcher H, Pichler F, Abenhaim L. Nordon C, et al. Among authors: karcher h. Value Health. 2014 Nov;17(7):A586. doi: 10.1016/j.jval.2014.08.1998. Epub 2014 Oct 26. Value Health. 2014. PMID: 27201991 Free article. No abstract available.

4

Trial exclusion criteria and their impact on the estimation of antipsychotic drugs effect: A case study using the SOHO database.

Nordon C, Bovagnet T, Belger M, Jimenez J, Olivares R, Chevrou-Severac H, Verdoux H, Haro JM, Abenhaim L, Karcher H; IMI GetReal WP2 group. Nordon C, et al. Among authors: karcher h. Schizophr Res. 2018 Mar;193:146-153. doi: 10.1016/j.schres.2017.07.031. Epub 2017 Jul 13. Schizophr Res. 2018. PMID: 28712965 Review.

5

Cabozantinib versus everolimus, nivolumab, axitinib, sorafenib and best supportive care: A network meta-analysis of progression-free survival and overall survival in second line treatment of advanced renal cell carcinoma.

Amzal B, Fu S, Meng J, Lister J, Karcher H. Amzal B, et al. Among authors: karcher h. PLoS One. 2017 Sep 8;12(9):e0184423. doi: 10.1371/journal.pone.0184423. eCollection 2017. PLoS One. 2017. PMID: 28886175 Free PMC article.

6

Second-line cabozantinib versus nivolumab in advanced renal cell carcinoma: Systematic review and indirect treatment comparison.

Porta C, Szczylik C, Casciano R, Fu S, Amzal B, Lister J, Karcher H, Meng J, Neumann M, Dinet J. Porta C, et al. Among authors: karcher h. Crit Rev Oncol Hematol. 2019 Jul;139:143-148. doi: 10.1016/j.critrevonc.2018.10.004. Epub 2018 Oct 24. Crit Rev Oncol Hematol. 2019. PMID: 30401604 Free article.

7

Ethical and social implications of using predictive modeling for Alzheimer's disease prevention: a systematic literature review protocol.

Angehrn Z, Nordon C, Turner A, Gove D, Karcher H, Keenan A, Neumann M, Sostar J, de Reydet de Vulpillieres F. Angehrn Z, et al. Among authors: karcher h. BMJ Open. 2019 Mar 3;9(3):e026468. doi: 10.1136/bmjopen-2018-026468. BMJ Open. 2019. PMID: 30833325 Free PMC article.

8

Ethical and Social Implications of Using Predictive Modeling for Alzheimer's Disease Prevention: A Systematic Literature Review.

Angehrn Z, Sostar J, Nordon C, Turner A, Gove D, Karcher H, Keenan A, Mittelstadt B, de Reydet-de Vulpillieres F. Angehrn Z, et al. Among authors: karcher h. J Alzheimers Dis. 2020;76(3):923-940. doi: 10.3233/JAD-191159. J Alzheimers Dis. 2020. PMID: 32597799

9

Testing the "RCT augmentation" methodology: A trial simulation study to guide the broadening of trials eligibility criteria and inform on effectiveness.

Nordon C, Sanchez B, Zhang M, Wang X, Hunt P, Belger M, Karcher H; GetReal Initiative. Nordon C, et al. Among authors: karcher h. Contemp Clin Trials Commun. 2023 Apr 14;33:101142. doi: 10.1016/j.conctc.2023.101142. eCollection 2023 Jun. Contemp Clin Trials Commun. 2023. PMID: 37397428 Free PMC article.

10

Nivolumab versus Cabozantinib: Comparing Overall Survival in Metastatic Renal Cell Carcinoma.

Wiecek W, Karcher H. Wiecek W, et al. Among authors: karcher h. PLoS One. 2016 Jun 6;11(6):e0155389. doi: 10.1371/journal.pone.0155389. eCollection 2016. PLoS One. 2016. PMID: 27271250 Free PMC article.

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