Accordi B - Search Results

1

EB-3D a novel choline kinase inhibitor induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells.

Mariotto E, Bortolozzi R, Volpin I, Carta D, Serafin V, Accordi B, Basso G, Navarro PL, López-Cara LC, Viola G. Mariotto E, et al. Among authors: accordi b. Biochem Pharmacol. 2018 Sep;155:213-223. doi: 10.1016/j.bcp.2018.07.004. Epub 2018 Jul 11. Biochem Pharmacol. 2018. PMID: 30006194

2

Ribociclib, a Cdk4/Cdk6 kinase inhibitor, enhances glucocorticoid sensitivity in B-acute lymphoblastic leukemia (B-All).

Bortolozzi R, Mattiuzzo E, Trentin L, Accordi B, Basso G, Viola G. Bortolozzi R, et al. Among authors: accordi b. Biochem Pharmacol. 2018 Jul;153:230-241. doi: 10.1016/j.bcp.2018.01.050. Epub 2018 Feb 3. Biochem Pharmacol. 2018. PMID: 29408328

3

Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer.

Mariotto E, Viola G, Ronca R, Persano L, Aveic S, Bhujwalla ZM, Mori N, Accordi B, Serafin V, López-Cara LC, Bortolozzi R. Mariotto E, et al. Among authors: accordi b. Cancers (Basel). 2018 Oct 22;10(10):391. doi: 10.3390/cancers10100391. Cancers (Basel). 2018. PMID: 30360374 Free PMC article.

4

AMPK inhibition enhances apoptosis in MLL-rearranged pediatric B-acute lymphoblastic leukemia cells.

Accordi B, Galla L, Milani G, Curtarello M, Serafin V, Lissandron V, Viola G, te Kronnie G, De Maria R, Petricoin EF 3rd, Liotta LA, Indraccolo S, Basso G. Accordi B, et al. Leukemia. 2013 Apr;27(5):1019-27. doi: 10.1038/leu.2012.338. Epub 2012 Nov 21. Leukemia. 2013. PMID: 23228943

5

Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia.

Serafin V, Capuzzo G, Milani G, Minuzzo SA, Pinazza M, Bortolozzi R, Bresolin S, Porcù E, Frasson C, Indraccolo S, Basso G, Accordi B. Serafin V, et al. Among authors: accordi b. Blood. 2017 Dec 21;130(25):2750-2761. doi: 10.1182/blood-2017-05-784603. Epub 2017 Nov 3. Blood. 2017. PMID: 29101238 Free article.

6

SYK Targeting Represents a Potential Therapeutic Option for Relapsed Resistant Pediatric ETV6-RUNX1 B-Acute Lymphoblastic Leukemia Patients.

Serafin V, Porcù E, Cortese G, Mariotto E, Veltri G, Bresolin S, Basso G, Accordi B. Serafin V, et al. Among authors: accordi b. Int J Mol Sci. 2019 Dec 7;20(24):6175. doi: 10.3390/ijms20246175. Int J Mol Sci. 2019. PMID: 31817853 Free PMC article.

7

Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.

Bertacchini J, Guida M, Accordi B, Mediani L, Martelli AM, Barozzi P, Petricoin E 3rd, Liotta L, Milani G, Giordan M, Luppi M, Forghieri F, De Pol A, Cocco L, Basso G, Marmiroli S. Bertacchini J, et al. Among authors: accordi b. Leukemia. 2014 Nov;28(11):2197-205. doi: 10.1038/leu.2014.123. Epub 2014 Apr 4. Leukemia. 2014. PMID: 24699302

8

Targeting BAG-1: a novel strategy to increase drug efficacy in acute myeloid leukemia.

Aveic S, Viola G, Accordi B, Micalizzi C, Santoro N, Masetti R, Locatelli F, Basso G, Pigazzi M. Aveic S, et al. Among authors: accordi b. Exp Hematol. 2015 Mar;43(3):180-190.e6. doi: 10.1016/j.exphem.2014.10.016. Epub 2014 Nov 11. Exp Hematol. 2015. PMID: 25461257 Free article.

9

Hepatocyte growth factor receptor c-MET is associated with FAS and when activated enhances drug-induced apoptosis in pediatric B acute lymphoblastic leukemia with TEL-AML1 translocation.

Accordi B, Pillozzi S, Dell'Orto MC, Cazzaniga G, Arcangeli A, Kronnie GT, Basso G. Accordi B, et al. J Biol Chem. 2007 Oct 5;282(40):29384-93. doi: 10.1074/jbc.M706314200. Epub 2007 Aug 2. J Biol Chem. 2007. PMID: 17673463 Free article.

10

Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.

Serafin V, Lissandron V, Buldini B, Bresolin S, Paganin M, Grillo F, Andriano N, Palmi C, Cazzaniga G, Marmiroli S, Conter V, Basso G, Accordi B. Serafin V, et al. Among authors: accordi b. Leukemia. 2017 Apr;31(4):1007-1011. doi: 10.1038/leu.2017.13. Epub 2017 Jan 13. Leukemia. 2017. PMID: 28082737 No abstract available.

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