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Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
Jimenez-Vargas NN, Pattison LA, Zhao P, Lieu T, Latorre R, Jensen DD, Castro J, Aurelio L, Le GT, Flynn B, Herenbrink CK, Yeatman HR, Edgington-Mitchell L, Porter CJH, Halls ML, Canals M, Veldhuis NA, Poole DP, McLean P, Hicks GA, Scheff N, Chen E, Bhattacharya A, Schmidt BL, Brierley SM, Vanner SJ, Bunnett NW. Jimenez-Vargas NN, et al. Among authors: le gt. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7438-E7447. doi: 10.1073/pnas.1721891115. Epub 2018 Jul 16. Proc Natl Acad Sci U S A. 2018. PMID: 30012612 Free PMC article.
A refined agonist pharmacophore for protease activated receptor 2.
Barry GD, Suen JY, Low HB, Pfeiffer B, Flanagan B, Halili M, Le GT, Fairlie DP. Barry GD, et al. Among authors: le gt. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5552-7. doi: 10.1016/j.bmcl.2007.08.026. Epub 2007 Aug 16. Bioorg Med Chem Lett. 2007. PMID: 17765542
75 results