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745 results

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Page 1
Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing.
Smith LJ, Wright J, Clark G, Ul-Hasan T, Jin X, Fong A, Chandra M, St Martin T, Rubin H, Knowlton D, Ellsworth JL, Fong Y, Wong KK Jr, Chatterjee S. Smith LJ, et al. Among authors: rubin h. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7379-E7388. doi: 10.1073/pnas.1802343115. Epub 2018 Jul 17. Proc Natl Acad Sci U S A. 2018. PMID: 30018062 Free PMC article.
Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates.
Ellsworth JL, Gingras J, Smith LJ, Rubin H, Seabrook TA, Patel K, Zapata N, Olivieri K, O'Callaghan M, Chlipala E, Morales P, Seymour A. Ellsworth JL, et al. Among authors: rubin h. PLoS One. 2019 Nov 26;14(11):e0225582. doi: 10.1371/journal.pone.0225582. eCollection 2019. PLoS One. 2019. PMID: 31770409 Free PMC article.
Sustained Correction of a Murine Model of Phenylketonuria following a Single Intravenous Administration of AAVHSC15-PAH.
Ahmed SS, Rubin H, Wang M, Faulkner D, Sengooba A, Dollive SN, Avila N, Ellsworth JL, Lamppu D, Lobikin M, Lotterhand J, Adamson-Small L, Wright T, Seymour A, Francone OL. Ahmed SS, et al. Among authors: rubin h. Mol Ther Methods Clin Dev. 2020 Mar 13;17:568-580. doi: 10.1016/j.omtm.2020.03.009. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32258219 Free PMC article.
Aurintricarboxylic acid increases yield of HSV-1 vectors.
Pechan P, Ardinger J, Ketavarapu J, Rubin H, Wadsworth SC, Scaria A. Pechan P, et al. Among authors: rubin h. Mol Ther Methods Clin Dev. 2014 Feb 19;1:6. doi: 10.1038/mtm.2013.6. eCollection 2014. Mol Ther Methods Clin Dev. 2014. PMID: 26015945 Free PMC article.
Inhibition of choroidal neovascularization in a nonhuman primate model by intravitreal administration of an AAV2 vector expressing a novel anti-VEGF molecule.
Lukason M, DuFresne E, Rubin H, Pechan P, Li Q, Kim I, Kiss S, Flaxel C, Collins M, Miller J, Hauswirth W, Maclachlan T, Wadsworth S, Scaria A. Lukason M, et al. Among authors: rubin h. Mol Ther. 2011 Feb;19(2):260-5. doi: 10.1038/mt.2010.230. Epub 2010 Oct 26. Mol Ther. 2011. PMID: 20978476 Free PMC article.
Bone marrow stromal cell-mediated gene therapy for hemophilia A: in vitro expression of human factor VIII with high biological activity requires the inclusion of the proteolytic site at amino acid 1648.
Chiang GG, Rubin HL, Cherington V, Wang T, Sobolewski J, McGrath CA, Gaffney A, Emami S, Sarver N, Levine PH, Greenberger JS, Hurwitz DR. Chiang GG, et al. Among authors: rubin hl. Hum Gene Ther. 1999 Jan 1;10(1):61-76. doi: 10.1089/10430349950019192. Hum Gene Ther. 1999. PMID: 10022531
Science-policy research collaborations need philosophers.
Schneider MD, Sogbanmu TO, Rubin H, Bortolus A, Chukwu EE, Heesen R, Hewitt CL, Kaufer R, Metzen H, Mitova V, Schwenkenbecher A, Schwindt E, Slanickova H, Woolaston K, Yu LA. Schneider MD, et al. Among authors: rubin h. Nat Hum Behav. 2024 Jun;8(6):1001-1002. doi: 10.1038/s41562-024-01892-x. Nat Hum Behav. 2024. PMID: 38750141 No abstract available.
745 results