Bünemann M - Search Results

1

Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization.

Miess E, Gondin AB, Yousuf A, Steinborn R, Mösslein N, Yang Y, Göldner M, Ruland JG, Bünemann M, Krasel C, Christie MJ, Halls ML, Schulz S, Canals M. Miess E, et al. Among authors: bunemann m. Sci Signal. 2018 Jul 17;11(539):eaas9609. doi: 10.1126/scisignal.aas9609. Sci Signal. 2018. PMID: 30018083

2

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells.

Vilardaga JP, Bünemann M, Krasel C, Castro M, Lohse MJ. Vilardaga JP, et al. Among authors: bunemann m. Nat Biotechnol. 2003 Jul;21(7):807-12. doi: 10.1038/nbt838. Epub 2003 Jun 15. Nat Biotechnol. 2003. PMID: 12808462

3

Kinetics of G-protein-coupled receptor signalling and desensitization.

Krasel C, Vilardaga JP, Bünemann M, Lohse MJ. Krasel C, et al. Among authors: bunemann m. Biochem Soc Trans. 2004 Dec;32(Pt 6):1029-31. doi: 10.1042/BST0321029. Biochem Soc Trans. 2004. PMID: 15506955

4

Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation.

Krasel C, Bünemann M, Lorenz K, Lohse MJ. Krasel C, et al. Among authors: bunemann m. J Biol Chem. 2005 Mar 11;280(10):9528-35. doi: 10.1074/jbc.M413078200. Epub 2005 Jan 5. J Biol Chem. 2005. PMID: 15634674 Free article.

5

A polymorphism-specific "memory" mechanism in the β(2)-adrenergic receptor.

Ahles A, Rochais F, Frambach T, Bünemann M, Engelhardt S. Ahles A, et al. Among authors: bunemann m. Sci Signal. 2011 Aug 9;4(185):ra53. doi: 10.1126/scisignal.2001681. Sci Signal. 2011. PMID: 21868359

6

The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively.

Al-Sabah S, Al-Fulaij M, Shaaban G, Ahmed HA, Mann RJ, Donnelly D, Bünemann M, Krasel C. Al-Sabah S, et al. Among authors: bunemann m. PLoS One. 2014 Sep 5;9(9):e106890. doi: 10.1371/journal.pone.0106890. eCollection 2014. PLoS One. 2014. PMID: 25191754 Free PMC article.

7

Influence of gαq on the dynamics of m3-acetylcholine receptor-g-protein-coupled receptor kinase 2 interaction.

Wolters V, Krasel C, Brockmann J, Bünemann M. Wolters V, et al. Among authors: bunemann m. Mol Pharmacol. 2015 Jan;87(1):9-17. doi: 10.1124/mol.114.094722. Epub 2014 Oct 14. Mol Pharmacol. 2015. PMID: 25316767

8

Engineered hyperphosphorylation of the β2-adrenoceptor prolongs arrestin-3 binding and induces arrestin internalization.

Zindel D, Butcher AJ, Al-Sabah S, Lanzerstorfer P, Weghuber J, Tobin AB, Bünemann M, Krasel C. Zindel D, et al. Among authors: bunemann m. Mol Pharmacol. 2015 Feb;87(2):349-62. doi: 10.1124/mol.114.095422. Epub 2014 Nov 25. Mol Pharmacol. 2015. PMID: 25425623 Free PMC article.

9

Interhelical interaction and receptor phosphorylation regulate the activation kinetics of different human β1-adrenoceptor variants.

Ahles A, Rodewald F, Rochais F, Bünemann M, Engelhardt S. Ahles A, et al. Among authors: bunemann m. J Biol Chem. 2015 Jan 16;290(3):1760-9. doi: 10.1074/jbc.M114.607333. Epub 2014 Dec 1. J Biol Chem. 2015. PMID: 25451930 Free PMC article.

10

The mode of agonist binding to a G protein-coupled receptor switches the effect that voltage changes have on signaling.

Rinne A, Mobarec JC, Mahaut-Smith M, Kolb P, Bünemann M. Rinne A, et al. Among authors: bunemann m. Sci Signal. 2015 Nov 3;8(401):ra110. doi: 10.1126/scisignal.aac7419. Sci Signal. 2015. PMID: 26535008

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