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Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization.
Sci Signal. 2018 Jul 17;11(539):eaas9609. doi: 10.1126/scisignal.aas9609.
Sci Signal. 2018.
PMID: 30018083
Voltage modulates the effect of μ-receptor activation in a ligand-dependent manner.
Ruland JG, Kirchhofer SB, Klindert S, Bailey CP, Bünemann M.
Ruland JG, et al.
Br J Pharmacol. 2020 Aug;177(15):3489-3504. doi: 10.1111/bph.15070. Epub 2020 May 19.
Br J Pharmacol. 2020.
PMID: 32297669
Free PMC article.
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Differential interaction patterns of opioid analgesics with µ opioid receptors correlate with ligand-specific voltage sensitivity.
Kirchhofer SB, Lim VJY, Ernst S, Karsai N, Ruland JG, Canals M, Kolb P, Bünemann M.
Kirchhofer SB, et al. Among authors: ruland jg.
Elife. 2023 Nov 20;12:e91291. doi: 10.7554/eLife.91291.
Elife. 2023.
PMID: 37983079
Free PMC article.
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