Ernst M - Search Results

1

SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2- Benzodiazepine Site.

Siebert DCB, Wieder M, Schlener L, Scholze P, Boresch S, Langer T, Schnürch M, Mihovilovic MD, Richter L, Ernst M, Ecker GF. Siebert DCB, et al. Among authors: ernst m. J Chem Inf Model. 2018 Aug 27;58(8):1682-1696. doi: 10.1021/acs.jcim.8b00199. Epub 2018 Aug 8. J Chem Inf Model. 2018. PMID: 30028134

2

Comparative modeling of GABA(A) receptors: limits, insights, future developments.

Ernst M, Brauchart D, Boresch S, Sieghart W. Ernst M, et al. Neuroscience. 2003;119(4):933-43. doi: 10.1016/s0306-4522(03)00288-4. Neuroscience. 2003. PMID: 12831854 Review.

3

Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.

Ogris W, Pöltl A, Hauer B, Ernst M, Oberto A, Wulff P, Höger H, Wisden W, Sieghart W. Ogris W, et al. Among authors: ernst m. Biochem Pharmacol. 2004 Oct 15;68(8):1621-9. doi: 10.1016/j.bcp.2004.07.020. Biochem Pharmacol. 2004. PMID: 15451405

4

Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function.

Ernst M, Bruckner S, Boresch S, Sieghart W. Ernst M, et al. Mol Pharmacol. 2005 Nov;68(5):1291-300. doi: 10.1124/mol.105.015982. Epub 2005 Aug 15. Mol Pharmacol. 2005. PMID: 16103045

5

An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.

Clayton T, Chen JL, Ernst M, Richter L, Cromer BA, Morton CJ, Ng H, Kaczorowski CC, Helmstetter FJ, Furtmüller R, Ecker G, Parker MW, Sieghart W, Cook JM. Clayton T, et al. Among authors: ernst m. Curr Med Chem. 2007;14(26):2755-75. doi: 10.2174/092986707782360097. Curr Med Chem. 2007. PMID: 18045122 Review.

6

Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands.

Richter L, de Graaf C, Sieghart W, Varagic Z, Mörzinger M, de Esch IJ, Ecker GF, Ernst M. Richter L, et al. Among authors: ernst m. Nat Chem Biol. 2012 Mar 25;8(5):455-64. doi: 10.1038/nchembio.917. Nat Chem Biol. 2012. PMID: 22446838 Free PMC article.

7

Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface.

Varagic Z, Wimmer L, Schnürch M, Mihovilovic MD, Huang S, Rallapalli S, Cook JM, Mirheydari P, Ecker GF, Sieghart W, Ernst M. Varagic Z, et al. Among authors: ernst m. Br J Pharmacol. 2013 May;169(2):371-83. doi: 10.1111/bph.12151. Br J Pharmacol. 2013. PMID: 23472852 Free PMC article.

8

Subtype selectivity of α+β- site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors.

Varagic Z, Ramerstorfer J, Huang S, Rallapalli S, Sarto-Jackson I, Cook J, Sieghart W, Ernst M. Varagic Z, et al. Among authors: ernst m. Br J Pharmacol. 2013 May;169(2):384-99. doi: 10.1111/bph.12153. Br J Pharmacol. 2013. PMID: 23472935 Free PMC article.

9

Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β₂ subunit of GABA(A) receptors.

Baur R, Kielar M, Richter L, Ernst M, Ecker GF, Sigel E. Baur R, et al. Among authors: ernst m. J Neurochem. 2013 Jul;126(1):29-36. doi: 10.1111/jnc.12270. Epub 2013 May 3. J Neurochem. 2013. PMID: 23600744 Free article.

10

Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β- Site.

Mirheydari P, Ramerstorfer J, Varagic Z, Scholze P, Wimmer L, Mihovilovic MM, Sieghart W, Ernst M. Mirheydari P, et al. Among authors: ernst m. Neurochem Res. 2014 Jun;39(6):1057-1067. doi: 10.1007/s11064-013-1156-3. Epub 2013 Sep 26. Neurochem Res. 2014. PMID: 24072672 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

2,210 results

Search Page

Filters