Ma X - Search Results

1

Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer.

Yi Y, Wang L, Zhao D, Huang S, Wang C, Liu Z, Sun H, Liu K, Ma X, Li Y. Yi Y, et al. Among authors: ma x. Chem Biol Drug Des. 2018 Dec;92(6):1988-1997. doi: 10.1111/cbdd.13370. Epub 2018 Aug 26. Chem Biol Drug Des. 2018. PMID: 30030903

2

Design, synthesis and biological evaluation of peptidyl epoxyketone proteasome inhibitors composed of β-amino acids.

Zhang J, Han M, Ma X, Xu L, Cao J, Zhou Y, Li J, Liu T, Hu Y. Zhang J, et al. Among authors: ma x. Chem Biol Drug Des. 2014 Nov;84(5):497-504. doi: 10.1111/cbdd.12342. Epub 2014 Jun 3. Chem Biol Drug Des. 2014. PMID: 24751157

3

Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

Yu H, Li Y, Ge Y, Song Z, Wang C, Huang S, Jin Y, Han X, Zhen Y, Liu K, Zhou Y, Ma X. Yu H, et al. Among authors: ma x. Eur J Med Chem. 2016 Mar 3;110:195-203. doi: 10.1016/j.ejmech.2016.01.045. Epub 2016 Jan 26. Eur J Med Chem. 2016. PMID: 26829280

4

Challenges and Perspectives on the Development of Small-Molecule EGFR Inhibitors against T790M-Mediated Resistance in Non-Small-Cell Lung Cancer.

Song Z, Ge Y, Wang C, Huang S, Shu X, Liu K, Zhou Y, Ma X. Song Z, et al. Among authors: ma x. J Med Chem. 2016 Jul 28;59(14):6580-94. doi: 10.1021/acs.jmedchem.5b00840. Epub 2016 Feb 26. J Med Chem. 2016. PMID: 26882288

5

P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate.

Jia Y, Liu Z, Wang C, Meng Q, Huo X, Liu Q, Sun H, Sun P, Yang X, Ma X, Liu K. Jia Y, et al. Among authors: ma x. Toxicol Appl Pharmacol. 2016 Sep 1;306:27-35. doi: 10.1016/j.taap.2016.06.030. Epub 2016 Jul 1. Toxicol Appl Pharmacol. 2016. PMID: 27377006

6

Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

Song Z, Jin Y, Ge Y, Wang C, Zhang J, Tang Z, Peng J, Liu K, Li Y, Ma X. Song Z, et al. Among authors: ma x. Bioorg Med Chem. 2016 Nov 1;24(21):5505-5512. doi: 10.1016/j.bmc.2016.09.001. Epub 2016 Sep 3. Bioorg Med Chem. 2016. PMID: 27634676

7

Novel Selective and Potent EGFR Inhibitor that Overcomes T790M-Mediated Resistance in Non-Small Cell Lung Cancer.

Li Y, Song Z, Jin Y, Tang Z, Kang J, Ma X. Li Y, et al. Among authors: ma x. Molecules. 2016 Nov 2;21(11):1462. doi: 10.3390/molecules21111462. Molecules. 2016. PMID: 27827863 Free PMC article.

8

Synthesis and biological evaluation of benzophenone derivatives as potential HIV-1 inhibitors.

Song Z, Wang P, Huang S, Wang C, Wang R, Yang L, Zhen Y, Liu K, Zheng Y, Ma X. Song Z, et al. Among authors: ma x. Med Chem. 2016 Nov 11. Online ahead of print. Med Chem. 2016. PMID: 27834135

9

Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.

Zhao D, Huang S, Qu M, Wang C, Liu Z, Li Z, Peng J, Liu K, Li Y, Ma X, Shu X. Zhao D, et al. Among authors: ma x. Eur J Med Chem. 2017 Jan 27;126:444-455. doi: 10.1016/j.ejmech.2016.11.047. Epub 2016 Nov 23. Eur J Med Chem. 2017. PMID: 27912175

10

Design and synthesis of phosphoryl-substituted diphenylpyrimidines (Pho-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors: Targeted treatment of B lymphoblastic leukemia cell lines.

Ge Y, Yang H, Wang C, Meng Q, Li L, Sun H, Zhen Y, Liu K, Li Y, Ma X. Ge Y, et al. Among authors: ma x. Bioorg Med Chem. 2017 Jan 15;25(2):765-772. doi: 10.1016/j.bmc.2016.11.054. Epub 2016 Nov 29. Bioorg Med Chem. 2017. PMID: 27956037

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