Wood DK - Search Results

1

Oxygen-dependent flow of sickle trait blood as an in vitro therapeutic benchmark for sickle cell disease treatments.

Lu X, Chaudhury A, Higgins JM, Wood DK. Lu X, et al. Among authors: wood dk. Am J Hematol. 2018 Oct;93(10):1227-1235. doi: 10.1002/ajh.25227. Epub 2018 Aug 21. Am J Hematol. 2018. PMID: 30033564 Free PMC article.

2

A biophysical indicator of vaso-occlusive risk in sickle cell disease.

Wood DK, Soriano A, Mahadevan L, Higgins JM, Bhatia SN. Wood DK, et al. Sci Transl Med. 2012 Feb 29;4(123):123ra26. doi: 10.1126/scitranslmed.3002738. Sci Transl Med. 2012. PMID: 22378926 Free PMC article.

3

Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension.

Lu X, Wood DK, Higgins JM. Lu X, et al. Among authors: wood dk. Biophys J. 2016 Jun 21;110(12):2751-2758. doi: 10.1016/j.bpj.2016.04.050. Biophys J. 2016. PMID: 27332133 Free PMC article.

4

A microfluidic platform to study the effects of vascular architecture and oxygen gradients on sickle blood flow.

Lu X, Galarneau MM, Higgins JM, Wood DK. Lu X, et al. Among authors: wood dk. Microcirculation. 2017 Jul;24(5):10.1111/micc.12357. doi: 10.1111/micc.12357. Microcirculation. 2017. PMID: 28129479 Free PMC article. Review.

5

Extracellular fluid tonicity impacts sickle red blood cell deformability and adhesion.

Carden MA, Fay ME, Lu X, Mannino RG, Sakurai Y, Ciciliano JC, Hansen CE, Chonat S, Joiner CH, Wood DK, Lam WA. Carden MA, et al. Among authors: wood dk. Blood. 2017 Dec 14;130(24):2654-2663. doi: 10.1182/blood-2017-04-780635. Epub 2017 Oct 4. Blood. 2017. PMID: 28978568 Free PMC article.

6

High-throughput assessment of hemoglobin polymer in single red blood cells from sickle cell patients under controlled oxygen tension.

Di Caprio G, Schonbrun E, Gonçalves BP, Valdez JM, Wood DK, Higgins JM. Di Caprio G, et al. Among authors: wood dk. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25236-25242. doi: 10.1073/pnas.1914056116. Epub 2019 Nov 25. Proc Natl Acad Sci U S A. 2019. PMID: 31767751 Free PMC article.

7

A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood.

Valdez JM, Datta YH, Higgins JM, Wood DK. Valdez JM, et al. Among authors: wood dk. APL Bioeng. 2019 Nov 15;3(4):046102. doi: 10.1063/1.5118212. eCollection 2019 Dec. APL Bioeng. 2019. PMID: 31803859 Free PMC article.

8

5-(Hydroxymethyl)furfural restores low-oxygen rheology of sickle trait blood in vitro.

Hansen S, Wood DK, Higgins JM. Hansen S, et al. Among authors: wood dk. Br J Haematol. 2020 Mar;188(6):985-993. doi: 10.1111/bjh.16251. Epub 2019 Dec 30. Br J Haematol. 2020. PMID: 31889311 Free PMC article.

9

An Experimental-Computational Approach to Quantify Blood Rheology in Sickle Cell Disease.

Bazzi MS, Valdez JM, Barocas VH, Wood DK. Bazzi MS, et al. Among authors: wood dk. Biophys J. 2020 Dec 1;119(11):2307-2315. doi: 10.1016/j.bpj.2020.10.011. Epub 2020 Oct 20. Biophys J. 2020. PMID: 33096079 Free PMC article.

10

MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease.

Demers M, Sturtevant S, Guertin KR, Gupta D, Desai K, Vieira BF, Li W, Hicks A, Ismail A, Gonçalves BP, Di Caprio G, Schonbrun E, Hansen S, Musayev FN, Safo MK, Wood DK, Higgins JM, Light DR. Demers M, et al. Among authors: wood dk. Blood Adv. 2021 Mar 9;5(5):1388-1402. doi: 10.1182/bloodadvances.2020003670. Blood Adv. 2021. PMID: 33661300 Free PMC article.

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