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Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis.
Maruyama T, Baba T, Maemoto Y, Hara-Miyauchi C, Hasegawa-Ogawa M, Okano HJ, Enda Y, Matsumoto K, Arimitsu N, Nakao K, Hamamoto H, Sekimizu K, Ohto-Nakanishi T, Nakanishi H, Tokuyama T, Yanagi S, Tagaya M, Tani K. Maruyama T, et al. Among authors: enda y. Cell Death Dis. 2018 Jul 23;9(8):797. doi: 10.1038/s41419-018-0815-3. Cell Death Dis. 2018. PMID: 30038238 Free PMC article.