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The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG.
Ye H, Minhajuddin M, Krug A, Pei S, Chou CH, Culp-Hill R, Ponder J, De Bloois E, Schniedewind B, Amaya ML, Inguva A, Stevens BM, Pollyea DA, Christians U, Grimes HL, D'Alessandro A, Jordan CT. Ye H, et al. Cancer Discov. 2021 Feb;11(2):500-519. doi: 10.1158/2159-8290.CD-20-0318. Epub 2020 Oct 7. Cancer Discov. 2021. PMID: 33028621 Free PMC article.
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer.
Oatman N, Dasgupta N, Arora P, Choi K, Gawali MV, Gupta N, Parameswaran S, Salomone J, Reisz JA, Lawler S, Furnari F, Brennan C, Wu J, Sallans L, Gudelsky G, Desai P, Gebelein B, Weirauch MT, D'Alessandro A, Komurov K, Dasgupta B. Oatman N, et al. Sci Adv. 2021 Feb 10;7(7):eabd7459. doi: 10.1126/sciadv.abd7459. Print 2021 Feb. Sci Adv. 2021. PMID: 33568479 Free PMC article.
In situ mapping identifies distinct vascular niches for myelopoiesis.
Zhang J, Wu Q, Johnson CB, Pham G, Kinder JM, Olsson A, Slaughter A, May M, Weinhaus B, D'Alessandro A, Engel JD, Jiang JX, Kofron JM, Huang LF, Prasath VBS, Way SS, Salomonis N, Grimes HL, Lucas D. Zhang J, et al. Nature. 2021 Feb;590(7846):457-462. doi: 10.1038/s41586-021-03201-2. Epub 2021 Feb 10. Nature. 2021. PMID: 33568812 Free PMC article.
Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.
Jones CL, Stevens BM, D'Alessandro A, Reisz JA, Culp-Hill R, Nemkov T, Pei S, Khan N, Adane B, Ye H, Krug A, Reinhold D, Smith C, DeGregori J, Pollyea DA, Jordan CT. Jones CL, et al. Cancer Cell. 2018 Nov 12;34(5):724-740.e4. doi: 10.1016/j.ccell.2018.10.005. Cancer Cell. 2018. PMID: 30423294 Free PMC article.
Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.
Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, Jordan CT, Hansen KC, D'Alessandro A, DeGregori J. Gregory MA, et al. Clin Cancer Res. 2019 Jul 1;25(13):4079-4090. doi: 10.1158/1078-0432.CCR-18-3223. Epub 2019 Apr 2. Clin Cancer Res. 2019. PMID: 30940653 Free PMC article.
1,340 results