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Page 1
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity.
Hassan R, Friebel A, Brackhagen L, Hobloss Z, Myllys M, González D, Albrecht W, Mohammed ESI, Seddek AL, Marchan R, Cadenas C, Cramer B, Humpf HU, Hartl L, Simbrunner B, Reiberger T, Trauner M, Hoehme S, Degen GH, Hengstler JG, Ghallab A. Hassan R, et al. Among authors: hengstler jg. Arch Toxicol. 2022 Nov;96(11):2967-2981. doi: 10.1007/s00204-022-03361-8. Epub 2022 Aug 13. Arch Toxicol. 2022. PMID: 35962801 Free PMC article.
The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity.
Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P. Campos G, et al. Among authors: hengstler jg. Arch Toxicol. 2014 Jun;88(6):1267-80. doi: 10.1007/s00204-014-1240-8. Epub 2014 Apr 20. Arch Toxicol. 2014. PMID: 24748426
Optimality in the zonation of ammonia detoxification in rodent liver.
Bartl M, Pfaff M, Ghallab A, Driesch D, Henkel SG, Hengstler JG, Schuster S, Kaleta C, Gebhardt R, Zellmer S, Li P. Bartl M, et al. Among authors: hengstler jg. Arch Toxicol. 2015 Nov;89(11):2069-78. doi: 10.1007/s00204-015-1596-4. Epub 2015 Oct 5. Arch Toxicol. 2015. PMID: 26438405
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.
Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG. Godoy P, et al. Among authors: hengstler jg. Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23. Arch Toxicol. 2016. PMID: 27339419 Free PMC article.
Adverse outcome pathways: opportunities, limitations and open questions.
Leist M, Ghallab A, Graepel R, Marchan R, Hassan R, Bennekou SH, Limonciel A, Vinken M, Schildknecht S, Waldmann T, Danen E, van Ravenzwaay B, Kamp H, Gardner I, Godoy P, Bois FY, Braeuning A, Reif R, Oesch F, Drasdo D, Höhme S, Schwarz M, Hartung T, Braunbeck T, Beltman J, Vrieling H, Sanz F, Forsby A, Gadaleta D, Fisher C, Kelm J, Fluri D, Ecker G, Zdrazil B, Terron A, Jennings P, van der Burg B, Dooley S, Meijer AH, Willighagen E, Martens M, Evelo C, Mombelli E, Taboureau O, Mantovani A, Hardy B, Koch B, Escher S, van Thriel C, Cadenas C, Kroese D, van de Water B, Hengstler JG. Leist M, et al. Among authors: hengstler jg. Arch Toxicol. 2017 Nov;91(11):3477-3505. doi: 10.1007/s00204-017-2045-3. Epub 2017 Oct 19. Arch Toxicol. 2017. PMID: 29051992 Review.
Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood.
Ghallab A, Hofmann U, Sezgin S, Vartak N, Hassan R, Zaza A, Godoy P, Schneider KM, Guenther G, Ahmed YA, Abbas AA, Keitel V, Kuepfer L, Dooley S, Lammert F, Trautwein C, Spiteller M, Drasdo D, Hofmann AF, Jansen PLM, Hengstler JG, Reif R. Ghallab A, et al. Among authors: hengstler jg. Hepatology. 2019 Feb;69(2):666-683. doi: 10.1002/hep.30213. Epub 2018 Nov 19. Hepatology. 2019. PMID: 30102412 Free PMC article.
562 results