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Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy.
Marini KD, Croucher DR, McCloy RA, Vaghjiani V, Gonzalez-Rajal A, Hastings JF, Chin V, Szczepny A, Kostyrko K, Marquez C, Jayasekara WSN, Alamgeer M, Boolell V, Han JZR, Waugh T, Lee HC, Oakes SR, Kumar B, Harrison CA, Hedger MP, Lorensuhewa N, Kita B, Barrow R, Robinson BW, de Kretser DM, Wu J, Ganju V, Sweet-Cordero EA, Burgess A, Martelotto LG, Rossello FJ, Cain JE, Watkins DN. Marini KD, et al. Among authors: oakes sr. Sci Transl Med. 2018 Jul 25;10(451):eaat3504. doi: 10.1126/scitranslmed.aat3504. Sci Transl Med. 2018. PMID: 30045976
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib.
Young AI, Law AM, Castillo L, Chong S, Cullen HD, Koehler M, Herzog S, Brummer T, Lee EF, Fairlie WD, Lucas MC, Herrmann D, Allam A, Timpson P, Watkins DN, Millar EK, O'Toole SA, Gallego-Ortega D, Ormandy CJ, Oakes SR. Young AI, et al. Among authors: oakes sr. Breast Cancer Res. 2016 Dec 8;18(1):125. doi: 10.1186/s13058-016-0781-6. Breast Cancer Res. 2016. PMID: 27931239 Free PMC article.
Andy's Algorithms: new automated digital image analysis pipelines for FIJI.
Law AMK, Yin JXM, Castillo L, Young AIJ, Piggin C, Rogers S, Caldon CE, Burgess A, Millar EKA, O'Toole SA, Gallego-Ortega D, Ormandy CJ, Oakes SR. Law AMK, et al. Among authors: oakes sr. Sci Rep. 2017 Nov 16;7(1):15717. doi: 10.1038/s41598-017-15885-6. Sci Rep. 2017. PMID: 29146920 Free PMC article.
MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma.
Castillo L, Young AIJ, Mawson A, Schafranek P, Steinmann AM, Nessem D, Parkin A, Johns A, Chou A, Law AMK, Lucas MC, Murphy KJ, Deng N, Gallego-Ortega D, Caldon CE; Australian Pancreatic Cancer Genome Initiative (APGI); Timpson P, Pajic M, Ormandy CJ, Oakes SR. Castillo L, et al. Among authors: oakes sr. Oncogene. 2020 Feb;39(8):1821-1829. doi: 10.1038/s41388-019-1091-0. Epub 2019 Nov 18. Oncogene. 2020. PMID: 31735913 Free PMC article.
ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.
Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhtyak Z, Cho C, Allerdice SL, Lee HJ, Valdes-Mora F, Herrmann D, Salomon R, Young AI, Lee BY, Sergio CM, Kaplan W, Piggin C, Conway JR, Rabinovich B, Millar EK, Oakes SR, Chtanova T, Swarbrick A, Naylor MJ, O'Toole S, Green AR, Timpson P, Gee JM, Ellis IO, Clark SJ, Ormandy CJ. Gallego-Ortega D, et al. Among authors: oakes sr. PLoS Biol. 2015 Dec 30;13(12):e1002330. doi: 10.1371/journal.pbio.1002330. eCollection 2015 Dec. PLoS Biol. 2015. PMID: 26717410 Free PMC article.
A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.
Oakes SR, Gallego-Ortega D, Stanford PM, Junankar S, Au WWY, Kikhtyak Z, von Korff A, Sergio CM, Law AMK, Castillo LE, Allerdice SL, Young AIJ, Piggin C, Whittle B, Bertram E, Naylor MJ, Roden DL, Donovan J, Korennykh A, Goodnow CC, O'Bryan MK, Ormandy CJ. Oakes SR, et al. PLoS Genet. 2017 Nov 8;13(11):e1007072. doi: 10.1371/journal.pgen.1007072. eCollection 2017 Nov. PLoS Genet. 2017. PMID: 29117179 Free PMC article.
Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies.
Liang Y, Jeganathan S, Marastoni S, Sharp A, Figueiredo I, Marcellus R, Mawson A, Shalev Z, Pesic A, Sweet J, Guo H, Uehling D, Gurel B, Neeb A, He HH, Montgomery B, Koritzinsky M, Oakes S, de Bono JS, Gleave M, Zoubeidi A, Wouters BG, Joshua AM. Liang Y, et al. Clin Cancer Res. 2021 Apr 15;27(8):2340-2351. doi: 10.1158/1078-0432.CCR-20-3260. Epub 2021 Feb 4. Clin Cancer Res. 2021. PMID: 33542074
49 results