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PPARγ partial agonist LPSF/GQ-16 prevents dermal and pulmonary fibrosis in HOCl-induced systemic sclerosis (SSc) and modulates cytokine production in PBMC of SSc patients.
de Almeida AR, Dantas AT, de Oliveira Gonçalves ME, Chêne C, Jeljeli M, Chouzenoux S, Thomas M, Cunha EGC, de Azevedo Valadares LD, de Melo Gomes JV, de Paula SKS, da Rocha Pitta MG, da Rocha Pitta I, de Melo Rêgo MJB, Pereira MC, Duarte ALBP, Abdalla DSP, Nicco C, Batteux F, da Rocha Pitta MG. de Almeida AR, et al. Among authors: nicco c. Inflammopharmacology. 2024 Feb;32(1):433-446. doi: 10.1007/s10787-023-01296-9. Epub 2023 Jul 21. Inflammopharmacology. 2024. PMID: 37477795
IBPA a mutual prodrug of ibuprofen and acetaminophen alleviates inflammation, immune dysregulation and fibrosis in preclinical models of systemic sclerosis.
Rodrigues de Almeida A, Jaime Bezerra Mendonça Junior F, Tavares Dantas A, Eduarda de Oliveira Gonçalves M, Chêne C, Jeljeli M, Chouzenoux S, Thomas M, David de Azevedo Valadares L, Andreza Bezerra Correia M, Ângela da Silva Alves W, Carvalho Lira E, Doridot L, Jesus Barreto de Melo Rêgo M, Cristiny Pereira M, Luzia Branco Pinto Duarte A, Saes Parra Abdalla D, Nicco C, Batteux F, Galdino da Rocha Pitta M. Rodrigues de Almeida A, et al. Among authors: nicco c. Int Immunopharmacol. 2024 Jul 30;136:112344. doi: 10.1016/j.intimp.2024.112344. Epub 2024 Jun 3. Int Immunopharmacol. 2024. PMID: 38833846
Microbiota medicine: towards clinical revolution.
Gebrayel P, Nicco C, Al Khodor S, Bilinski J, Caselli E, Comelli EM, Egert M, Giaroni C, Karpinski TM, Loniewski I, Mulak A, Reygner J, Samczuk P, Serino M, Sikora M, Terranegra A, Ufnal M, Villeger R, Pichon C, Konturek P, Edeas M. Gebrayel P, et al. Among authors: nicco c. J Transl Med. 2022 Mar 7;20(1):111. doi: 10.1186/s12967-022-03296-9. J Transl Med. 2022. PMID: 35255932 Free PMC article. Review.
103 results