Novel probabilistic models of spatial genetic ancestry with applications to stratification correction in genome-wide association studies.
Bhaskar A, Javanmard A, Courtade TA, Tse D.
Bhaskar A, et al.
Bioinformatics. 2017 Mar 15;33(6):879-885. doi: 10.1093/bioinformatics/btw720.
Bioinformatics. 2017.
PMID: 28025204
Free PMC article.
We also develop an association test that uses the ancestry coordinates inferred by GAP to accurately account for ancestry-induced correlations in GWAS. Based on simulations and analysis of a dataset of 10 metabolic traits measured in a Northern Finland cohort, which …
We also develop an association test that uses the ancestry coordinates inferred by GAP to accurately account for ancestry-induced correlatio …