Schlaepfer IR - Search Results

1

RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers.

Pathak GP, Shah R, Kennedy BE, Murphy JP, Clements D, Konda P, Giacomantonio M, Xu Z, Schlaepfer IR, Gujar S. Pathak GP, et al. Among authors: schlaepfer ir. Mol Ther. 2018 Aug 1;26(8):2019-2033. doi: 10.1016/j.ymthe.2018.05.026. Epub 2018 Jun 30. Mol Ther. 2018. PMID: 30078441 Free PMC article.

2

Lipid catabolism via CPT1 as a therapeutic target for prostate cancer.

Schlaepfer IR, Rider L, Rodrigues LU, Gijón MA, Pac CT, Romero L, Cimic A, Sirintrapun SJ, Glodé LM, Eckel RH, Cramer SD. Schlaepfer IR, et al. Mol Cancer Ther. 2014 Oct;13(10):2361-71. doi: 10.1158/1535-7163.MCT-14-0183. Epub 2014 Aug 13. Mol Cancer Ther. 2014. PMID: 25122071 Free PMC article.

3

Exosomes secreted by placental stem cells selectively inhibit growth of aggressive prostate cancer cells.

Peak TC, Praharaj PP, Panigrahi GK, Doyle M, Su Y, Schlaepfer IR, Singh R, Vander Griend DJ, Alickson J, Hemal A, Atala A, Deep G. Peak TC, et al. Among authors: schlaepfer ir. Biochem Biophys Res Commun. 2018 May 23;499(4):1004-1010. doi: 10.1016/j.bbrc.2018.04.038. Epub 2018 Apr 9. Biochem Biophys Res Commun. 2018. PMID: 29627574 Free PMC article.

4

Targeting Fatty Acid Oxidation to Promote Anoikis and Inhibit Ovarian Cancer Progression.

Sawyer BT, Qamar L, Yamamoto TM, McMellen A, Watson ZL, Richer JK, Behbakht K, Schlaepfer IR, Bitler BG. Sawyer BT, et al. Among authors: schlaepfer ir. Mol Cancer Res. 2020 Jul;18(7):1088-1098. doi: 10.1158/1541-7786.MCR-19-1057. Epub 2020 Mar 20. Mol Cancer Res. 2020. PMID: 32198139 Free PMC article.

5

Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis.

Deep G, Schlaepfer IR. Deep G, et al. Among authors: schlaepfer ir. Int J Mol Sci. 2016 Jul 2;17(7):1061. doi: 10.3390/ijms17071061. Int J Mol Sci. 2016. PMID: 27384557 Free PMC article. Review.

6

Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity.

Guth A, Monk E, Agarwal R, Bergman BC, Zemski-Berry KA, Minic A, Jordan K, Schlaepfer IR. Guth A, et al. Among authors: schlaepfer ir. Int J Mol Sci. 2020 Dec 18;21(24):9660. doi: 10.3390/ijms21249660. Int J Mol Sci. 2020. PMID: 33352903 Free PMC article.

7

Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxel.

Schlaepfer IR, Hitz CA, Gijón MA, Bergman BC, Eckel RH, Jacobsen BM. Schlaepfer IR, et al. Mol Cell Endocrinol. 2012 Nov 5;363(1-2):111-21. doi: 10.1016/j.mce.2012.08.005. Epub 2012 Aug 16. Mol Cell Endocrinol. 2012. PMID: 22922095 Free PMC article.

8

Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation.

Schlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep G. Schlaepfer IR, et al. Oncotarget. 2015 Sep 8;6(26):22836-56. doi: 10.18632/oncotarget.4479. Oncotarget. 2015. PMID: 26087400 Free PMC article.

9

Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts.

Schlaepfer IR, Glodé LM, Hitz CA, Pac CT, Boyle KE, Maroni P, Deep G, Agarwal R, Lucia SM, Cramer SD, Serkova NJ, Eckel RH. Schlaepfer IR, et al. Mol Imaging Biol. 2015 Aug;17(4):529-38. doi: 10.1007/s11307-014-0814-4. Mol Imaging Biol. 2015. PMID: 25561013 Free PMC article.

10

Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade.

Flaig TW, Salzmann-Sullivan M, Su LJ, Zhang Z, Joshi M, Gijón MA, Kim J, Arcaroli JJ, Van Bokhoven A, Lucia MS, La Rosa FG, Schlaepfer IR. Flaig TW, et al. Among authors: schlaepfer ir. Oncotarget. 2017 Apr 21;8(34):56051-56065. doi: 10.18632/oncotarget.17359. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915573 Free PMC article.

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