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328 results

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A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.
Jun HJ, Appleman VA, Wu HJ, Rose CM, Pineda JJ, Yeo AT, Delcuze B, Lee C, Gyuris A, Zhu H, Woolfenden S, Bronisz A, Nakano I, Chiocca EA, Bronson RT, Ligon KL, Sarkaria JN, Gygi SP, Michor F, Mitchison TJ, Charest A. Jun HJ, et al. Among authors: ligon kl. Nat Commun. 2018 Aug 6;9(1):3116. doi: 10.1038/s41467-018-05036-4. Nat Commun. 2018. PMID: 30082792 Free PMC article.
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. Zheng H, et al. Among authors: ligon kl. Nature. 2008 Oct 23;455(7216):1129-33. doi: 10.1038/nature07443. Nature. 2008. PMID: 18948956 Free PMC article.
Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group.
Alexander BM, Galanis E, Yung WK, Ballman KV, Boyett JM, Cloughesy TF, Degroot JF, Huse JT, Mann B, Mason W, Mellinghoff IK, Mikkelsen T, Mischel PS, O'Neill BP, Prados MD, Sarkaria JN, Tawab-Amiri A, Trippa L, Ye X, Ligon KL, Berry DA, Wen PY. Alexander BM, et al. Among authors: ligon kl. Neuro Oncol. 2015 Feb;17(2):180-8. doi: 10.1093/neuonc/nou154. Epub 2014 Aug 26. Neuro Oncol. 2015. PMID: 25165194 Free PMC article. Review.
A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K.
Ma DJ, Galanis E, Anderson SK, Schiff D, Kaufmann TJ, Peller PJ, Giannini C, Brown PD, Uhm JH, McGraw S, Jaeckle KA, Flynn PJ, Ligon KL, Buckner JC, Sarkaria JN. Ma DJ, et al. Among authors: ligon kl. Neuro Oncol. 2015 Sep;17(9):1261-9. doi: 10.1093/neuonc/nou328. Epub 2014 Dec 18. Neuro Oncol. 2015. PMID: 25526733 Free PMC article. Clinical Trial.
Intermediate DNA methylation is a conserved signature of genome regulation.
Elliott G, Hong C, Xing X, Zhou X, Li D, Coarfa C, Bell RJ, Maire CL, Ligon KL, Sigaroudinia M, Gascard P, Tlsty TD, Harris RA, Schalkwyk LC, Bilenky M, Mill J, Farnham PJ, Kellis M, Marra MA, Milosavljevic A, Hirst M, Stormo GD, Wang T, Costello JF. Elliott G, et al. Among authors: ligon kl. Nat Commun. 2015 Feb 18;6:6363. doi: 10.1038/ncomms7363. Nat Commun. 2015. PMID: 25691127 Free PMC article.
Hypofractionated versus standard radiation therapy with or without temozolomide for older glioblastoma patients.
Arvold ND, Tanguturi SK, Aizer AA, Wen PY, Reardon DA, Lee EQ, Nayak L, Christianson LW, Horvath MC, Dunn IF, Golby AJ, Johnson MD, Claus EB, Chiocca EA, Ligon KL, Alexander BM. Arvold ND, et al. Among authors: ligon kl. Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):384-9. doi: 10.1016/j.ijrobp.2015.01.017. Epub 2015 Apr 1. Int J Radiat Oncol Biol Phys. 2015. PMID: 25841623
328 results