Schiefer A - Search Results

1

Effective inhibition of rifampicin-resistant Chlamydia trachomatis by the novel DNA-dependent RNA polymerase inhibitor corallopyronin A.

Shima K, Ledig S, Loeper N, Schiefer A, Pfarr K, Hoerauf A, Graspeuntner S, Rupp J. Shima K, et al. Among authors: schiefer a. Int J Antimicrob Agents. 2018 Oct;52(4):523-524. doi: 10.1016/j.ijantimicag.2018.07.025. Epub 2018 Aug 6. Int J Antimicrob Agents. 2018. PMID: 30092271 No abstract available.

2

Functional conservation of the lipid II biosynthesis pathway in the cell wall-less bacteria Chlamydia and Wolbachia: why is lipid II needed?

Henrichfreise B, Schiefer A, Schneider T, Nzukou E, Poellinger C, Hoffmann TJ, Johnston KL, Moelleken K, Wiedemann I, Pfarr K, Hoerauf A, Sahl HG. Henrichfreise B, et al. Among authors: schiefer a. Mol Microbiol. 2009 Sep;73(5):913-23. doi: 10.1111/j.1365-2958.2009.06815.x. Epub 2009 Jul 28. Mol Microbiol. 2009. PMID: 19656295 Free article.

3

Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo.

Schiefer A, Schmitz A, Schäberle TF, Specht S, Lämmer C, Johnston KL, Vassylyev DG, König GM, Hoerauf A, Pfarr K. Schiefer A, et al. J Infect Dis. 2012 Jul 15;206(2):249-57. doi: 10.1093/infdis/jis341. Epub 2012 May 14. J Infect Dis. 2012. PMID: 22586066 Free PMC article.

4

Requirement of lipid II biosynthesis for cell division in cell wall-less Wolbachia, endobacteria of arthropods and filarial nematodes.

Vollmer J, Schiefer A, Schneider T, Jülicher K, Johnston KL, Taylor MJ, Sahl HG, Hoerauf A, Pfarr K. Vollmer J, et al. Among authors: schiefer a. Int J Med Microbiol. 2013 Apr;303(3):140-9. doi: 10.1016/j.ijmm.2013.01.002. Epub 2013 Mar 19. Int J Med Microbiol. 2013. PMID: 23517690

5

The ClpP peptidase of Wolbachia endobacteria is a novel target for drug development against filarial infections.

Schiefer A, Vollmer J, Lämmer C, Specht S, Lentz C, Ruebsamen-Schaeff H, Brötz-Oesterhelt H, Hoerauf A, Pfarr K. Schiefer A, et al. J Antimicrob Chemother. 2013 Aug;68(8):1790-800. doi: 10.1093/jac/dkt105. Epub 2013 Apr 12. J Antimicrob Chemother. 2013. PMID: 23584755

6

Corallopyronin A - a promising antibiotic for treatment of filariasis.

Schäberle TF, Schiefer A, Schmitz A, König GM, Hoerauf A, Pfarr K. Schäberle TF, et al. Among authors: schiefer a. Int J Med Microbiol. 2014 Jan;304(1):72-8. doi: 10.1016/j.ijmm.2013.08.010. Epub 2013 Sep 4. Int J Med Microbiol. 2014. PMID: 24079981 Review.

7

Insights into Structure-Activity Relationships of Bacterial RNA Polymerase Inhibiting Corallopyronin Derivatives.

Schäberle TF, Schmitz A, Zocher G, Schiefer A, Kehraus S, Neu E, Roth M, Vassylyev DG, Stehle T, Bierbaum G, Hoerauf A, Pfarr K, König GM. Schäberle TF, et al. Among authors: schiefer a. J Nat Prod. 2015 Oct 23;78(10):2505-9. doi: 10.1021/acs.jnatprod.5b00175. Epub 2015 Oct 2. J Nat Prod. 2015. PMID: 26431157

8

NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae.

Ajendra J, Specht S, Ziewer S, Schiefer A, Pfarr K, Parčina M, Kufer TA, Hoerauf A, Hübner MP. Ajendra J, et al. Among authors: schiefer a. Sci Rep. 2016 Dec 22;6:39648. doi: 10.1038/srep39648. Sci Rep. 2016. PMID: 28004792 Free PMC article.

9

AmiD Is a Novel Peptidoglycan Amidase in Wolbachia Endosymbionts of Drosophila melanogaster.

Wilmes M, Meier K, Schiefer A, Josten M, Otten CF, Klöckner A, Henrichfreise B, Vollmer W, Hoerauf A, Pfarr K. Wilmes M, et al. Among authors: schiefer a. Front Cell Infect Microbiol. 2017 Aug 4;7:353. doi: 10.3389/fcimb.2017.00353. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 28824885 Free PMC article.

10

Orientia tsutsugamushi Is Highly Susceptible to the RNA Polymerase Switch Region Inhibitor Corallopyronin A In Vitro and In Vivo.

Kock F, Hauptmann M, Osterloh A, Schäberle TF, Poppert S, Frickmann H, Menzel KD, Peschel G, Pfarr K, Schiefer A, König GM, Hoerauf A, Fleischer B, Keller C. Kock F, et al. Among authors: schiefer a. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01732-17. doi: 10.1128/AAC.01732-17. Print 2018 Apr. Antimicrob Agents Chemother. 2018. PMID: 29358295 Free PMC article.

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