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Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites.
Marin-Mogollon C, van Pul FJA, Miyazaki S, Imai T, Ramesar J, Salman AM, Winkel BMF, Othman AS, Kroeze H, Chevalley-Maurel S, Reyes-Sandoval A, Roestenberg M, Franke-Fayard B, Janse CJ, Khan SM. Marin-Mogollon C, et al. Malar J. 2018 Aug 9;17(1):288. doi: 10.1186/s12936-018-2431-1. Malar J. 2018. PMID: 30092798 Free PMC article.
Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development.
Annoura T, van Schaijk BC, Ploemen IH, Sajid M, Lin JW, Vos MW, Dinmohamed AG, Inaoka DK, Rijpma SR, van Gemert GJ, Chevalley-Maurel S, Kiełbasa SM, Scheltinga F, Franke-Fayard B, Klop O, Hermsen CC, Kita K, Gego A, Franetich JF, Mazier D, Hoffman SL, Janse CJ, Sauerwein RW, Khan SM. Annoura T, et al. FASEB J. 2014 May;28(5):2158-70. doi: 10.1096/fj.13-241570. Epub 2014 Feb 7. FASEB J. 2014. PMID: 24509910
A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites.
van Schaijk BC, Ploemen IH, Annoura T, Vos MW, Foquet L, van Gemert GJ, Chevalley-Maurel S, van de Vegte-Bolmer M, Sajid M, Franetich JF, Lorthiois A, Leroux-Roels G, Meuleman P, Hermsen CC, Mazier D, Hoffman SL, Janse CJ, Khan SM, Sauerwein RW. van Schaijk BC, et al. Elife. 2014 Nov 19;3:e03582. doi: 10.7554/eLife.03582. Elife. 2014. PMID: 25407681 Free PMC article.
Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.
Lin JW, Spaccapelo R, Schwarzer E, Sajid M, Annoura T, Deroost K, Ravelli RB, Aime E, Capuccini B, Mommaas-Kienhuis AM, O'Toole T, Prins F, Franke-Fayard BM, Ramesar J, Chevalley-Maurel S, Kroeze H, Koster AJ, Tanke HJ, Crisanti A, Langhorne J, Arese P, Van den Steen PE, Janse CJ, Khan SM. Lin JW, et al. J Exp Med. 2015 Jun 1;212(6):893-903. doi: 10.1084/jem.20141731. Epub 2015 May 4. J Exp Med. 2015. PMID: 25941254 Free PMC article.
Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites.
Rijpma SR, van der Velden M, González-Pons M, Annoura T, van Schaijk BC, van Gemert GJ, van den Heuvel JJ, Ramesar J, Chevalley-Maurel S, Ploemen IH, Khan SM, Franetich JF, Mazier D, de Wilt JH, Serrano AE, Russel FG, Janse CJ, Sauerwein RW, Koenderink JB, Franke-Fayard BM. Rijpma SR, et al. Cell Microbiol. 2016 Mar;18(3):369-83. doi: 10.1111/cmi.12517. Epub 2015 Nov 10. Cell Microbiol. 2016. PMID: 26332724 Free PMC article.
Protective Efficacy Induced by Genetically Attenuated Mid-to-Late Liver-Stage Arresting Plasmodium berghei Δmrp2 Parasites.
van der Velden M, Rijpma SR, Verweij V, van Gemert GJ, Chevalley-Maurel S, van de Vegte-Bolmer M, Franke-Fayard BM, Russel FG, Janse CJ, Sauerwein RW, Koenderink JB. van der Velden M, et al. Am J Trop Med Hyg. 2016 Aug 3;95(2):378-82. doi: 10.4269/ajtmh.16-0226. Epub 2016 Jun 13. Am J Trop Med Hyg. 2016. PMID: 27296385 Free PMC article.
33 results