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Page 1
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding.
McDowell IC, Barrera A, D'Ippolito AM, Vockley CM, Hong LK, Leichter SM, Bartelt LC, Majoros WH, Song L, Safi A, Koçak DD, Gersbach CA, Hartemink AJ, Crawford GE, Engelhardt BE, Reddy TE. McDowell IC, et al. Genome Res. 2018 Sep;28(9):1272-1284. doi: 10.1101/gr.233346.117. Epub 2018 Aug 10. Genome Res. 2018. PMID: 30097539 Free PMC article.
Transversions have larger regulatory effects than transitions.
Guo C, McDowell IC, Nodzenski M, Scholtens DM, Allen AS, Lowe WL, Reddy TE. Guo C, et al. Among authors: mcdowell ic. BMC Genomics. 2017 May 19;18(1):394. doi: 10.1186/s12864-017-3785-4. BMC Genomics. 2017. PMID: 28525990 Free PMC article.
A long-range flexible billboard model of gene activation.
Vockley CM, McDowell IC, D'Ippolito AM, Reddy TE. Vockley CM, et al. Among authors: mcdowell ic. Transcription. 2017 Aug 8;8(4):261-267. doi: 10.1080/21541264.2017.1317694. Epub 2017 Jun 9. Transcription. 2017. PMID: 28598247 Free PMC article.
Genetic effects on gene expression across human tissues.
GTEx Consortium; Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group; Statistical Methods groups—Analysis Working Group; Enhancing GTEx (eGTEx) groups; NIH Common Fund; NIH/NCI; NIH/NHGRI; NIH/NIMH; NIH/NIDA; Biospecimen Collection Source Site—NDRI; Biospecimen Collection Source Site—RPCI; Biospecimen Core Resource—VARI; Brain Bank Repository—University of Miami Brain Endowment Bank; Leidos Biomedical—Project Management; ELSI Study; Genome Browser Data Integration &Visualization—EBI; Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz; Lead analysts:; Laboratory, Data Analysis &Coordinating Center (LDACC):; NIH program management:; Biospecimen collection:; Pathology:; eQTL manuscript working group:; Battle A, Brown CD, Engelhardt BE, Montgomery SB. GTEx Consortium, et al. Nature. 2017 Oct 11;550(7675):204-213. doi: 10.1038/nature24277. Nature. 2017. PMID: 29022597 Free PMC article.
Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids.
D'Ippolito AM, McDowell IC, Barrera A, Hong LK, Leichter SM, Bartelt LC, Vockley CM, Majoros WH, Safi A, Song L, Gersbach CA, Crawford GE, Reddy TE. D'Ippolito AM, et al. Among authors: mcdowell ic. Cell Syst. 2018 Aug 22;7(2):146-160.e7. doi: 10.1016/j.cels.2018.06.007. Epub 2018 Jul 18. Cell Syst. 2018. PMID: 30031775 Free article.
21 results