Cini E - Search Results

1

Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo.

Vesci L, Milazzo FM, Stasi MA, Pace S, Manera F, Tallarico C, Cini E, Petricci E, Manetti F, De Santis R, Giannini G. Vesci L, et al. Among authors: cini e. Eur J Med Chem. 2018 Sep 5;157:368-379. doi: 10.1016/j.ejmech.2018.07.053. Epub 2018 Jul 27. Eur J Med Chem. 2018. PMID: 30099257

2

Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation.

Botta CB, Cabri W, Cini E, De Cesare L, Fattorusso C, Giannini G, Persico M, Petrella A, Rondinelli F, Rodriquez M, Russo A, Taddei M. Botta CB, et al. Among authors: cini e. J Med Chem. 2011 Apr 14;54(7):2165-82. doi: 10.1021/jm101373a. Epub 2011 Mar 18. J Med Chem. 2011. PMID: 21417297

3

Domino reactions triggered by hydroformylation.

Petricci E, Cini E. Petricci E, et al. Among authors: cini e. Top Curr Chem. 2013;342:117-49. doi: 10.1007/128_2013_463. Top Curr Chem. 2013. PMID: 23912442

4

Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors.

Taddei M, Cini E, Giannotti L, Giannini G, Battistuzzi G, Vignola D, Vesci L, Cabri W. Taddei M, et al. Among authors: cini e. Bioorg Med Chem Lett. 2014 Jan 1;24(1):61-4. doi: 10.1016/j.bmcl.2013.11.072. Epub 2013 Dec 4. Bioorg Med Chem Lett. 2014. PMID: 24345446

5

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation.

Cini E, Faltoni V, Petricci E, Taddei M, Salvini L, Giannini G, Vesci L, Milazzo FM, Anastasi AM, Battistuzzi G, De Santis R. Cini E, et al. Chem Sci. 2018 Jul 3;9(31):6490-6496. doi: 10.1039/c7sc05266a. eCollection 2018 Aug 21. Chem Sci. 2018. PMID: 30288233 Free PMC article.

6

ErbB2 Targeted Epigenetic Modulation: Anti-tumor Efficacy of the ADC Trastuzumab-HDACi ST8176AA1.

Milazzo FM, Vesci L, Anastasi AM, Chiapparino C, Rosi A, Giannini G, Taddei M, Cini E, Faltoni V, Petricci E, Battistuzzi G, Salvini L, Carollo V, De Santis R. Milazzo FM, et al. Among authors: cini e. Front Oncol. 2020 Jan 23;9:1534. doi: 10.3389/fonc.2019.01534. eCollection 2019. Front Oncol. 2020. PMID: 32039017 Free PMC article.

7

Antibody drug conjugates with hydroxamic acid cargos for histone deacetylase (HDAC) inhibition.

Cianferotti C, Faltoni V, Cini E, Ermini E, Migliorini F, Petricci E, Taddei M, Salvini L, Battistuzzi G, Milazzo FM, Anastasi AM, Chiapparino C, De Santis R, Giannini G. Cianferotti C, et al. Among authors: cini e. Chem Commun (Camb). 2021 Jan 28;57(7):867-870. doi: 10.1039/d0cc06131j. Chem Commun (Camb). 2021. PMID: 33433550

8

Quinolines and Oxazino-quinoline Derivatives as Small Molecule GLI1 Inhibitors Identified by Virtual Screening.

Manetti F, Maresca L, Crivaro E, Pepe S, Cini E, Singh S, Governa P, Maramai S, Giannini G, Stecca B, Petricci E. Manetti F, et al. Among authors: cini e. ACS Med Chem Lett. 2022 Jul 22;13(8):1329-1336. doi: 10.1021/acsmedchemlett.2c00249. eCollection 2022 Aug 11. ACS Med Chem Lett. 2022. PMID: 35978701 Free PMC article.

9

Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor.

Tassone G, Mazzorana M, Mangani S, Petricci E, Cini E, Giannini G, Pozzi C, Maramai S. Tassone G, et al. Among authors: cini e. Int J Mol Sci. 2022 Aug 21;23(16):9458. doi: 10.3390/ijms23169458. Int J Mol Sci. 2022. PMID: 36012721 Free PMC article.

10

A pH-responsive crosslinker platform for antibody-drug conjugate (ADC) targeting delivery.

Migliorini F, Cini E, Dreassi E, Finetti F, Ievoli G, Macrì G, Petricci E, Rango E, Trabalzini L, Taddei M. Migliorini F, et al. Among authors: cini e. Chem Commun (Camb). 2022 Sep 20;58(75):10532-10535. doi: 10.1039/d2cc03052g. Chem Commun (Camb). 2022. PMID: 36043993

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