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TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.
Martini-Stoica H, Cole AL, Swartzlander DB, Chen F, Wan YW, Bajaj L, Bader DA, Lee VMY, Trojanowski JQ, Liu Z, Sardiello M, Zheng H. Martini-Stoica H, et al. Among authors: sardiello m. J Exp Med. 2018 Sep 3;215(9):2355-2377. doi: 10.1084/jem.20172158. Epub 2018 Aug 14. J Exp Med. 2018. PMID: 30108137 Free PMC article.
TFEB regulates lysosomal proteostasis.
Song W, Wang F, Savini M, Ake A, di Ronza A, Sardiello M, Segatori L. Song W, et al. Among authors: sardiello m. Hum Mol Genet. 2013 May 15;22(10):1994-2009. doi: 10.1093/hmg/ddt052. Epub 2013 Feb 7. Hum Mol Genet. 2013. PMID: 23393155 Free article.
mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.
Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M. Palmieri M, et al. Among authors: sardiello m. Nat Commun. 2017 Feb 6;8:14338. doi: 10.1038/ncomms14338. Nat Commun. 2017. PMID: 28165011 Free PMC article.
AKT modulates the autophagy-lysosome pathway via TFEB.
Palmieri M, Pal R, Sardiello M. Palmieri M, et al. Among authors: sardiello m. Cell Cycle. 2017 Jul 3;16(13):1237-1238. doi: 10.1080/15384101.2017.1337968. Epub 2017 Jun 21. Cell Cycle. 2017. PMID: 28636416 Free PMC article. No abstract available.
56 results