Bayly-Jones C - Search Results

1

The first transmembrane region of complement component-9 acts as a brake on its self-assembly.

Spicer BA, Law RHP, Caradoc-Davies TT, Ekkel SM, Bayly-Jones C, Pang SS, Conroy PJ, Ramm G, Radjainia M, Venugopal H, Whisstock JC, Dunstone MA. Spicer BA, et al. Nat Commun. 2018 Aug 15;9(1):3266. doi: 10.1038/s41467-018-05717-0. Nat Commun. 2018. PMID: 30111885 Free PMC article.

2

The mystery behind membrane insertion: a review of the complement membrane attack complex.

Bayly-Jones C, Bubeck D, Dunstone MA. Bayly-Jones C, et al. Philos Trans R Soc Lond B Biol Sci. 2017 Aug 5;372(1726):20160221. doi: 10.1098/rstb.2016.0221. Philos Trans R Soc Lond B Biol Sci. 2017. PMID: 28630159 Free PMC article. Review.

3

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.

Pang SS, Bayly-Jones C, Radjainia M, Spicer BA, Law RHP, Hodel AW, Parsons ES, Ekkel SM, Conroy PJ, Ramm G, Venugopal H, Bird PI, Hoogenboom BW, Voskoboinik I, Gambin Y, Sierecki E, Dunstone MA, Whisstock JC. Pang SS, et al. Nat Commun. 2019 Sep 19;10(1):4288. doi: 10.1038/s41467-019-12279-2. Nat Commun. 2019. PMID: 31537793 Free PMC article.

4

Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector.

Bayly-Jones C, Pang SS, Spicer BA, Whisstock JC, Dunstone MA. Bayly-Jones C, et al. Front Immunol. 2020 Oct 15;11:581906. doi: 10.3389/fimmu.2020.581906. eCollection 2020. Front Immunol. 2020. PMID: 33178209 Free PMC article. Review.

5

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor.

Bayly-Jones C, Lupton CJ, Fritz C, Venugopal H, Ramsbeck D, Wermann M, Jäger C, de Marco A, Schilling S, Schlenzig D, Whisstock JC. Bayly-Jones C, et al. Nat Commun. 2022 Oct 19;13(1):6178. doi: 10.1038/s41467-022-33893-7. Nat Commun. 2022. PMID: 36261433 Free PMC article.

6

The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1.

Lupton CJ, Bayly-Jones C, D'Andrea L, Huang C, Schittenhelm RB, Venugopal H, Whisstock JC, Halls ML, Ellisdon AM. Lupton CJ, et al. Among authors: bayly jones c. Nat Struct Mol Biol. 2021 Dec;28(12):982-988. doi: 10.1038/s41594-021-00687-2. Epub 2021 Dec 9. Nat Struct Mol Biol. 2021. PMID: 34887559

7

Mining folded proteomes in the era of accurate structure prediction.

Bayly-Jones C, Whisstock JC. Bayly-Jones C, et al. PLoS Comput Biol. 2022 Mar 25;18(3):e1009930. doi: 10.1371/journal.pcbi.1009930. eCollection 2022 Mar. PLoS Comput Biol. 2022. PMID: 35333855 Free PMC article.

8

Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.

Chang YG, Lupton CJ, Bayly-Jones C, Keen AC, D'Andrea L, Lucato CM, Steele JR, Venugopal H, Schittenhelm RB, Whisstock JC, Halls ML, Ellisdon AM. Chang YG, et al. Among authors: bayly jones c. Nat Struct Mol Biol. 2022 Aug;29(8):767-773. doi: 10.1038/s41594-022-00804-9. Epub 2022 Jul 21. Nat Struct Mol Biol. 2022. PMID: 35864164 Free PMC article.

9

Single-molecule analysis of the entire perfringolysin O pore formation pathway.

McGuinness C, Walsh JC, Bayly-Jones C, Dunstone MA, Christie MP, Morton CJ, Parker MW, Böcking T. McGuinness C, et al. Among authors: bayly jones c. Elife. 2022 Aug 24;11:e74901. doi: 10.7554/eLife.74901. Elife. 2022. PMID: 36000711 Free PMC article.

10

Challenges and approaches to studying pore-forming proteins.

Benton JT, Bayly-Jones C. Benton JT, et al. Among authors: bayly jones c. Biochem Soc Trans. 2021 Dec 17;49(6):2749-2765. doi: 10.1042/BST20210706. Biochem Soc Trans. 2021. PMID: 34747994 Free PMC article. Review.

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