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Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis.
Muradás TC, Abbadi BL, Villela AD, Macchi FS, Bergo PF, de Freitas TF, Sperotto NDM, Timmers LFSM, Norberto de Souza O, Picada JN, Fachini J, da Silva JB, de Albuquerque NCP, Habenschus MD, Carrão DB, Rocha BA, Barbosa Junior F, de Oliveira ARM, Mascarello A, Neuenfeldf P, Nunes RJ, Morbidoni HR, Campos MM, Basso LA, Rodrigues-Junior VS. Muradás TC, et al. Among authors: campos mm. PLoS One. 2018 Aug 16;13(8):e0202568. doi: 10.1371/journal.pone.0202568. eCollection 2018. PLoS One. 2018. PMID: 30114296 Free PMC article.
Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation.
Mielcke TR, Mascarello A, Filippi-Chiela E, Zanin RF, Lenz G, Leal PC, Chiaradia LD, Yunes RA, Nunes RJ, Battastini AM, Morrone FB, Campos MM. Mielcke TR, et al. Among authors: campos mm. Eur J Med Chem. 2012 Feb;48:255-64. doi: 10.1016/j.ejmech.2011.12.023. Epub 2011 Dec 22. Eur J Med Chem. 2012. PMID: 22209415
Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection.
Rodrigues-Junior VS, Dos Santos Junior A, Dos Santos AJ, Schneider CZ, Calixto JB, Sousa EH, de França Lopes LG, Souto AA, Basso LA, Santos DS, Campos MM. Rodrigues-Junior VS, et al. Among authors: campos mm. Int J Antimicrob Agents. 2012 Aug;40(2):182-5. doi: 10.1016/j.ijantimicag.2012.04.019. Epub 2012 Jun 27. Int J Antimicrob Agents. 2012. PMID: 22748570
IQG-607 abrogates the synthesis of mycolic acids and displays intracellular activity against Mycobacterium tuberculosis in infected macrophages.
Rodrigues-Junior VS, dos Santos Junior AA, Villela AD, Belardinelli JM, Morbidoni HR, Basso LA, Campos MM, Santos DS. Rodrigues-Junior VS, et al. Among authors: campos mm. Int J Antimicrob Agents. 2014 Jan;43(1):82-5. doi: 10.1016/j.ijantimicag.2013.08.021. Epub 2013 Oct 1. Int J Antimicrob Agents. 2014. PMID: 24139881
380 results