Ovaa H - Search Results

1

Native chemical ligation at methionine bioisostere norleucine allows for N-terminal chemical protein ligation.

Xin BT, van Tol BDM, Ovaa H, Geurink PP. Xin BT, et al. Among authors: ovaa h. Org Biomol Chem. 2018 Aug 29;16(34):6306-6315. doi: 10.1039/c8ob01627e. Org Biomol Chem. 2018. PMID: 30117511

2

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Faesen AC, Luna-Vargas MP, Geurink PP, Clerici M, Merkx R, van Dijk WJ, Hameed DS, El Oualid F, Ovaa H, Sixma TK. Faesen AC, et al. Among authors: ovaa h. Chem Biol. 2011 Dec 23;18(12):1550-61. doi: 10.1016/j.chembiol.2011.10.017. Chem Biol. 2011. PMID: 22195557

3

A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents.

Geurink PP, El Oualid F, Jonker A, Hameed DS, Ovaa H. Geurink PP, et al. Among authors: ovaa h. Chembiochem. 2012 Jan 23;13(2):293-7. doi: 10.1002/cbic.201100706. Epub 2011 Dec 23. Chembiochem. 2012. PMID: 22213387 Free PMC article. No abstract available.

4

On terminal alkynes that can react with active-site cysteine nucleophiles in proteases.

Ekkebus R, van Kasteren SI, Kulathu Y, Scholten A, Berlin I, Geurink PP, de Jong A, Goerdayal S, Neefjes J, Heck AJ, Komander D, Ovaa H. Ekkebus R, et al. Among authors: ovaa h. J Am Chem Soc. 2013 Feb 27;135(8):2867-70. doi: 10.1021/ja309802n. Epub 2013 Feb 15. J Am Chem Soc. 2013. PMID: 23387960 Free PMC article.

5

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D. Mevissen TE, et al. Among authors: ovaa h. Cell. 2013 Jul 3;154(1):169-84. doi: 10.1016/j.cell.2013.05.046. Cell. 2013. PMID: 23827681 Free PMC article.

6

Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15.

Basters A, Geurink PP, El Oualid F, Ketscher L, Casutt MS, Krause E, Ovaa H, Knobeloch KP, Fritz G. Basters A, et al. Among authors: ovaa h. FEBS J. 2014 Apr;281(7):1918-28. doi: 10.1111/febs.12754. Epub 2014 Mar 3. FEBS J. 2014. PMID: 24533902 Free article.

7

A native chemical ligation handle that enables the synthesis of advanced activity-based probes: diubiquitin as a case study.

Mulder MP, El Oualid F, ter Beek J, Ovaa H. Mulder MP, et al. Among authors: ovaa h. Chembiochem. 2014 May 5;15(7):946-9. doi: 10.1002/cbic.201402012. Epub 2014 Mar 12. Chembiochem. 2014. PMID: 24623714 Free PMC article.

8

Catching a DUB in the act: novel ubiquitin-based active site directed probes.

Ekkebus R, Flierman D, Geurink PP, Ovaa H. Ekkebus R, et al. Among authors: ovaa h. Curr Opin Chem Biol. 2014 Dec;23:63-70. doi: 10.1016/j.cbpa.2014.10.005. Curr Opin Chem Biol. 2014. PMID: 25461387 Free PMC article. Review.

9

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition.

Banno A, Garcia DA, van Baarsel ED, Metz PJ, Fisch K, Widjaja CE, Kim SH, Lopez J, Chang AN, Geurink PP, Florea BI, Overkleeft HS, Ovaa H, Bui JD, Yang J, Chang JT. Banno A, et al. Among authors: ovaa h. Oncotarget. 2016 Apr 19;7(16):21527-41. doi: 10.18632/oncotarget.7596. Oncotarget. 2016. PMID: 26930717 Free PMC article.

10

Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes.

Geurink PP, van Tol BD, van Dalen D, Brundel PJ, Mevissen TE, Pruneda JN, Elliott PR, van Tilburg GB, Komander D, Ovaa H. Geurink PP, et al. Among authors: ovaa h. Chembiochem. 2016 May 3;17(9):816-20. doi: 10.1002/cbic.201600017. Epub 2016 Mar 21. Chembiochem. 2016. PMID: 26996281 Free PMC article.

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