Xin BT - Search Results

1

Native chemical ligation at methionine bioisostere norleucine allows for N-terminal chemical protein ligation.

Xin BT, van Tol BDM, Ovaa H, Geurink PP. Xin BT, et al. Org Biomol Chem. 2018 Aug 29;16(34):6306-6315. doi: 10.1039/c8ob01627e. Org Biomol Chem. 2018. PMID: 30117511

2

Total chemical synthesis of murine ISG15 and an activity-based probe with physiological binding properties.

Xin BT, Gan J, Fernandez DJ, Knobeloch KP, Geurink PP, Ovaa H. Xin BT, et al. Org Biomol Chem. 2019 Dec 28;17(48):10148-10152. doi: 10.1039/c9ob02127b. Epub 2019 Nov 11. Org Biomol Chem. 2019. PMID: 31710063

3

Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos.

Kooij R, Liu S, Sapmaz A, Xin BT, Janssen GMC, van Veelen PA, Ovaa H, Dijke PT, Geurink PP. Kooij R, et al. Among authors: xin bt. J Am Chem Soc. 2020 Sep 30;142(39):16825-16841. doi: 10.1021/jacs.0c07726. Epub 2020 Sep 18. J Am Chem Soc. 2020. PMID: 32886496 Free PMC article.

4

Exploring dual electrophiles in peptide-based proteasome inhibitors: carbonyls and epoxides.

Xin BT, de Bruin G, Verdoes M, Filippov DV, van der Marel GA, Overkleeft HS. Xin BT, et al. Org Biomol Chem. 2014 Aug 14;12(30):5710-8. doi: 10.1039/c4ob00893f. Epub 2014 Jun 26. Org Biomol Chem. 2014. PMID: 24968066

5

Proteasome Subunit Selective Activity-Based Probes Report on Proteasome Core Particle Composition in a Native Polyacrylamide Gel Electrophoresis Fluorescence-Resonance Energy Transfer Assay.

de Bruin G, Xin BT, Florea BI, Overkleeft HS. de Bruin G, et al. Among authors: xin bt. J Am Chem Soc. 2016 Aug 10;138(31):9874-80. doi: 10.1021/jacs.6b04207. Epub 2016 Jul 26. J Am Chem Soc. 2016. PMID: 27428761

6

Structure-Based Design of β5c Selective Inhibitors of Human Constitutive Proteasomes.

Xin BT, de Bruin G, Huber EM, Besse A, Florea BI, Filippov DV, van der Marel GA, Kisselev AF, van der Stelt M, Driessen C, Groll M, Overkleeft HS. Xin BT, et al. J Med Chem. 2016 Aug 11;59(15):7177-87. doi: 10.1021/acs.jmedchem.6b00705. Epub 2016 Aug 1. J Med Chem. 2016. PMID: 27438186

7

A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities.

de Bruin G, Xin BT, Kraus M, van der Stelt M, van der Marel GA, Kisselev AF, Driessen C, Florea BI, Overkleeft HS. de Bruin G, et al. Among authors: xin bt. Angew Chem Int Ed Engl. 2016 Mar 18;55(13):4199-203. doi: 10.1002/anie.201509092. Epub 2015 Oct 29. Angew Chem Int Ed Engl. 2016. PMID: 26511210

8

Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors.

Besse A, Besse L, Kraus M, Mendez-Lopez M, Bader J, Xin BT, de Bruin G, Maurits E, Overkleeft HS, Driessen C. Besse A, et al. Among authors: xin bt. Cell Chem Biol. 2019 Mar 21;26(3):340-351.e3. doi: 10.1016/j.chembiol.2018.11.007. Epub 2019 Jan 3. Cell Chem Biol. 2019. PMID: 30612952 Free article.

9

Development of new Malt1 inhibitors and probes.

Xin BT, Schimmack G, Du Y, Florea BI, van der Marel GA, Driessen C, Krappmann D, Overkleeft HS. Xin BT, et al. Bioorg Med Chem. 2016 Aug 1;24(15):3312-29. doi: 10.1016/j.bmc.2016.03.035. Epub 2016 Mar 28. Bioorg Med Chem. 2016. PMID: 27085674

10

Coordination-Assisted Bioorthogonal Chemistry: Orthogonal Tetrazine Ligation with Vinylboronic Acid and a Strained Alkene.

Eising S, Xin BT, Kleinpenning F, Heming JJA, Florea BI, Overkleeft HS, Bonger KM. Eising S, et al. Among authors: xin bt. Chembiochem. 2018 Aug 6;19(15):1648-1652. doi: 10.1002/cbic.201800275. Epub 2018 Jun 28. Chembiochem. 2018. PMID: 29806887

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