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dsRNA Sensing Induces Loss of Cell Identity.
Zhou R, Wang G, Kim D, Kim S, Islam N, Chen R, Wang Z, Li A, McCarthy EF, Li L, Hu Z, Garza LA. Zhou R, et al. Among authors: li l, li a. J Invest Dermatol. 2019 Jan;139(1):91-99. doi: 10.1016/j.jid.2018.07.021. Epub 2018 Aug 16. J Invest Dermatol. 2019. PMID: 30120933 Free PMC article.
Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3.
Kim D, Chen R, Sheu M, Kim N, Kim S, Islam N, Wier EM, Wang G, Li A, Park A, Son W, Evans B, Yu V, Prizmic VP, Oh E, Wang Z, Yu J, Huang W, Archer NK, Hu Z, Clemetson N, Nelson AM, Chien A, Okoye GA, Miller LS, Ghiaur G, Kang S, Jones JW, Kane MA, Garza LA. Kim D, et al. Among authors: li a. Nat Commun. 2019 Jun 26;10(1):2811. doi: 10.1038/s41467-019-10811-y. Nat Commun. 2019. PMID: 31243280 Free PMC article.
Bacteria induce skin regeneration via IL-1β signaling.
Wang G, Sweren E, Liu H, Wier E, Alphonse MP, Chen R, Islam N, Li A, Xue Y, Chen J, Park S, Chen Y, Lee S, Wang Y, Wang S, Archer NK, Andrews W, Kane MA, Dare E, Reddy SK, Hu Z, Grice EA, Miller LS, Garza LA. Wang G, et al. Among authors: li a. Cell Host Microbe. 2021 May 12;29(5):777-791.e6. doi: 10.1016/j.chom.2021.03.003. Epub 2021 Apr 1. Cell Host Microbe. 2021. PMID: 33798492 Free PMC article.
Neutrophil extracellular traps impair regeneration.
Wier E, Asada M, Wang G, Alphonse MP, Li A, Hintelmann C, Sweren E, Youn C, Pielstick B, Ortines R, Lyu C, Daskam M, Miller LS, Archer NK, Garza LA. Wier E, et al. Among authors: li a. J Cell Mol Med. 2021 Nov;25(21):10008-10019. doi: 10.1111/jcmm.16896. Epub 2021 Oct 8. J Cell Mol Med. 2021. PMID: 34623736 Free PMC article.
Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth.
Xue Y, Lyu C, Taylor A, Van Ee A, Kiemen A, Choi Y, Khavanian N, Henn D, Lee C, Hwang L, Wier E, Wang S, Lee S, Li A, Kirby C, Wang G, Wu PH, Wirtz D, Garza LA, Reddy SK. Xue Y, et al. Among authors: li a. Sci Adv. 2022 Apr 29;8(17):eabl8698. doi: 10.1126/sciadv.abl8698. Epub 2022 Apr 27. Sci Adv. 2022. PMID: 35476447 Free PMC article.
Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism.
Wang G, Sweren E, Andrews W, Li Y, Chen J, Xue Y, Wier E, Alphonse MP, Luo L, Miao Y, Chen R, Zeng D, Lee S, Li A, Dare E, Kim D, Archer NK, Reddy SK, Resar L, Hu Z, Grice EA, Kane MA, Garza LA. Wang G, et al. Among authors: li y, li a. Sci Adv. 2023 Jan 4;9(1):eabo7555. doi: 10.1126/sciadv.abo7555. Epub 2023 Jan 4. Sci Adv. 2023. PMID: 36598999 Free PMC article.
Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata.
Tsai J, Gori S, Alt J, Tiwari S, Iyer J, Talwar R, Hinsu D, Ahirwar K, Mohanty S, Khunt C, Sutariya B, Jani K, Venkatasubbaiah V, Patel A, Meghapara J, Joshi K, Sahu R, Rana V, Nigade P, Talluri RS, Murty KVSN, Joshi K, Ramanathan V, Li A, Islam N, Snajdr I, Majer P, Rais R, Slusher BS, Garza LA. Tsai J, et al. Among authors: li a. PNAS Nexus. 2022 Dec 16;2(1):pgac297. doi: 10.1093/pnasnexus/pgac297. eCollection 2023 Jan. PNAS Nexus. 2022. PMID: 36712931 Free PMC article.
The use of ectopic volar fibroblasts to modify skin identity.
Lee SS, Sweren E, Dare E, Derr P, Derr K, Wang CC, Hardesty B, Willis AA, Chen J, Vuillier JK, Du J, Wool J, Ruci A, Wang VY, Lee C, Iyengar S, Asami S, Daskam M, Lee C, Lee JC, Cho D, Kim J, Martinez-Peña EG, Lee SM, He X, Wakeman M, Sicilia I, Dobbs DT, van Ee A, Li A, Xue Y, Williams KL, Kirby CS, Kim D, Kim S, Xu L, Wang R, Ferrer M, Chen Y, Kang JU, Kalhor R, Kang S, Garza LA. Lee SS, et al. Among authors: li a. Science. 2024 Sep 6;385(6713):eadi1650. doi: 10.1126/science.adi1650. Epub 2024 Sep 6. Science. 2024. PMID: 39236183 Free PMC article.
GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1.
Zhong Y, Wang Z, Fu B, Pan F, Yachida S, Dhara M, Albesiano E, Li L, Naito Y, Vilardell F, Cummings C, Martinelli P, Li A, Yonescu R, Ma Q, Griffin CA, Real FX, Iacobuzio-Donahue CA. Zhong Y, et al. Among authors: li l, li a. PLoS One. 2011;6(7):e22129. doi: 10.1371/journal.pone.0022129. Epub 2011 Jul 19. PLoS One. 2011. PMID: 21811562 Free PMC article.
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