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Page 1
Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase.
Long JD, Lee JM, Aylward EH, Gillis T, Mysore JS, Abu Elneel K, Chao MJ, Paulsen JS, MacDonald ME, Gusella JF. Long JD, et al. Among authors: aylward eh. Am J Hum Genet. 2018 Sep 6;103(3):349-357. doi: 10.1016/j.ajhg.2018.07.017. Epub 2018 Aug 16. Am J Hum Genet. 2018. PMID: 30122542 Free PMC article.
Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset.
McAllister B, Donaldson J, Binda CS, Powell S, Chughtai U, Edwards G, Stone J, Lobanov S, Elliston L, Schuhmacher LN, Rees E, Menzies G, Ciosi M, Maxwell A, Chao MJ, Hong EP, Lucente D, Wheeler V, Lee JM, MacDonald ME, Long JD, Aylward EH, Landwehrmeyer GB, Rosser AE; REGISTRY Investigators of the European Huntington’s disease network; Paulsen JS; PREDICT-HD Investigators of the Huntington Study Group; Williams NM, Gusella JF, Monckton DG, Allen ND, Holmans P, Jones L, Massey TH. McAllister B, et al. Among authors: aylward eh. Nat Neurosci. 2022 Apr;25(4):446-457. doi: 10.1038/s41593-022-01033-5. Epub 2022 Apr 4. Nat Neurosci. 2022. PMID: 35379994 Free PMC article.
Prediction of manifest Huntington's disease with clinical and imaging measures: a prospective observational study.
Paulsen JS, Long JD, Ross CA, Harrington DL, Erwin CJ, Williams JK, Westervelt HJ, Johnson HJ, Aylward EH, Zhang Y, Bockholt HJ, Barker RA; PREDICT-HD Investigators and Coordinators of the Huntington Study Group. Paulsen JS, et al. Among authors: aylward eh. Lancet Neurol. 2014 Dec;13(12):1193-201. doi: 10.1016/S1474-4422(14)70238-8. Epub 2014 Nov 3. Lancet Neurol. 2014. PMID: 25453459 Free PMC article.
Detection of Huntington's disease decades before diagnosis: the Predict-HD study.
Paulsen JS, Langbehn DR, Stout JC, Aylward E, Ross CA, Nance M, Guttman M, Johnson S, MacDonald M, Beglinger LJ, Duff K, Kayson E, Biglan K, Shoulson I, Oakes D, Hayden M; Predict-HD Investigators and Coordinators of the Huntington Study Group. Paulsen JS, et al. J Neurol Neurosurg Psychiatry. 2008 Aug;79(8):874-80. doi: 10.1136/jnnp.2007.128728. Epub 2007 Dec 20. J Neurol Neurosurg Psychiatry. 2008. PMID: 18096682 Free PMC article.
Cerebral cortex structure in prodromal Huntington disease.
Nopoulos PC, Aylward EH, Ross CA, Johnson HJ, Magnotta VA, Juhl AR, Pierson RK, Mills J, Langbehn DR, Paulsen JS; PREDICT-HD Investigators Coordinators of Huntington Study Group (HSG). Nopoulos PC, et al. Among authors: aylward eh. Neurobiol Dis. 2010 Dec;40(3):544-54. doi: 10.1016/j.nbd.2010.07.014. Epub 2010 Aug 2. Neurobiol Dis. 2010. PMID: 20688164 Free PMC article.
Longitudinal change in regional brain volumes in prodromal Huntington disease.
Aylward EH, Nopoulos PC, Ross CA, Langbehn DR, Pierson RK, Mills JA, Johnson HJ, Magnotta VA, Juhl AR, Paulsen JS; PREDICT-HD Investigators and Coordinators of Huntington Study Group. Aylward EH, et al. J Neurol Neurosurg Psychiatry. 2011 Apr;82(4):405-10. doi: 10.1136/jnnp.2010.208264. Epub 2010 Sep 30. J Neurol Neurosurg Psychiatry. 2011. PMID: 20884680 Free PMC article.
Neurocognitive signs in prodromal Huntington disease.
Stout JC, Paulsen JS, Queller S, Solomon AC, Whitlock KB, Campbell JC, Carlozzi N, Duff K, Beglinger LJ, Langbehn DR, Johnson SA, Biglan KM, Aylward EH. Stout JC, et al. Among authors: aylward eh. Neuropsychology. 2011 Jan;25(1):1-14. doi: 10.1037/a0020937. Neuropsychology. 2011. PMID: 20919768 Free PMC article.
Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment.
Nopoulos PC, Aylward EH, Ross CA, Mills JA, Langbehn DR, Johnson HJ, Magnotta VA, Pierson RK, Beglinger LJ, Nance MA, Barker RA, Paulsen JS; PREDICT-HD Investigators and Coordinators of the Huntington Study Group. Nopoulos PC, et al. Among authors: aylward eh. Brain. 2011 Jan;134(Pt 1):137-42. doi: 10.1093/brain/awq280. Epub 2010 Oct 4. Brain. 2011. PMID: 20923788 Free PMC article.
150 results