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Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase.
Long JD, Lee JM, Aylward EH, Gillis T, Mysore JS, Abu Elneel K, Chao MJ, Paulsen JS, MacDonald ME, Gusella JF. Long JD, et al. Among authors: chao mj. Am J Hum Genet. 2018 Sep 6;103(3):349-357. doi: 10.1016/j.ajhg.2018.07.017. Epub 2018 Aug 16. Am J Hum Genet. 2018. PMID: 30122542 Free PMC article.
Sequence-Level Analysis of the Major European Huntington Disease Haplotype.
Lee JM, Kim KH, Shin A, Chao MJ, Abu Elneel K, Gillis T, Mysore JS, Kaye JA, Zahed H, Kratter IH, Daub AC, Finkbeiner S, Li H, Roach JC, Goodman N, Hood L, Myers RH, MacDonald ME, Gusella JF. Lee JM, et al. Among authors: chao mj. Am J Hum Genet. 2015 Sep 3;97(3):435-44. doi: 10.1016/j.ajhg.2015.07.017. Epub 2015 Aug 27. Am J Hum Genet. 2015. PMID: 26320893 Free PMC article.
Haplotype-based stratification of Huntington's disease.
Chao MJ, Gillis T, Atwal RS, Mysore JS, Arjomand J, Harold D, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF, Lee JM. Chao MJ, et al. Eur J Hum Genet. 2017 Nov;25(11):1202-1209. doi: 10.1038/ejhg.2017.125. Epub 2017 Aug 23. Eur J Hum Genet. 2017. PMID: 28832564 Free PMC article.
A modifier of Huntington's disease onset at the MLH1 locus.
Lee JM, Chao MJ, Harold D, Abu Elneel K, Gillis T, Holmans P, Jones L, Orth M, Myers RH, Kwak S, Wheeler VC, MacDonald ME, Gusella JF. Lee JM, et al. Among authors: chao mj. Hum Mol Genet. 2017 Oct 1;26(19):3859-3867. doi: 10.1093/hmg/ddx286. Hum Mol Genet. 2017. PMID: 28934397 Free PMC article.
Population-specific genetic modification of Huntington's disease in Venezuela.
Chao MJ, Kim KH, Shin JW, Lucente D, Wheeler VC, Li H, Roach JC, Hood L, Wexler NS, Jardim LB, Holmans P, Jones L, Orth M, Kwak S, MacDonald ME, Gusella JF, Lee JM. Chao MJ, et al. PLoS Genet. 2018 May 11;14(5):e1007274. doi: 10.1371/journal.pgen.1007274. eCollection 2018 May. PLoS Genet. 2018. PMID: 29750799 Free PMC article.
Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington's Disease.
Ellis N, Tee A, McAllister B, Massey T, McLauchlan D, Stone T, Correia K, Loupe J, Kim KH, Barker D, Hong EP, Chao MJ, Long JD, Lucente D, Vonsattel JPG, Pinto RM, Elneel KA, Ramos EM, Mysore JS, Gillis T, Wheeler VC, Medway C, Hall L, Kwak S, Sampaio C, Ciosi M, Maxwell A, Chatzi A, Monckton DG, Orth M, Landwehrmeyer GB, Paulsen JS, Shoulson I, Myers RH, van Duijn E, Rickards H, MacDonald ME, Lee JM, Gusella JF, Jones L, Holmans P. Ellis N, et al. Among authors: chao mj. Biol Psychiatry. 2020 May 1;87(9):857-865. doi: 10.1016/j.biopsych.2019.12.010. Epub 2019 Dec 17. Biol Psychiatry. 2020. PMID: 32087949 Free PMC article.
Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Kim KH, Hong EP, Shin JW, Chao MJ, Loupe J, Gillis T, Mysore JS, Holmans P, Jones L, Orth M, Monckton DG, Long JD, Kwak S, Lee R, Gusella JF, MacDonald ME, Lee JM. Kim KH, et al. Among authors: chao mj. Am J Hum Genet. 2020 Jul 2;107(1):96-110. doi: 10.1016/j.ajhg.2020.05.012. Epub 2020 Jun 25. Am J Hum Genet. 2020. PMID: 32589923 Free PMC article.
Association Analysis of Chromosome X to Identify Genetic Modifiers of Huntington's Disease.
Hong EP, Chao MJ, Massey T, McAllister B, Lobanov S, Jones L, Holmans P, Kwak S, Orth M, Ciosi M, Monckton DG, Long JD, Lucente D, Wheeler VC, MacDonald ME, Gusella JF, Lee JM. Hong EP, et al. Among authors: chao mj. J Huntingtons Dis. 2021;10(3):367-375. doi: 10.3233/JHD-210485. J Huntingtons Dis. 2021. PMID: 34180418 Free PMC article.
51 results