Hock AK - Search Results

1

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3.

Tajan M, Hock AK, Blagih J, Robertson NA, Labuschagne CF, Kruiswijk F, Humpton TJ, Adams PD, Vousden KH. Tajan M, et al. Among authors: hock ak. Cell Metab. 2018 Nov 6;28(5):721-736.e6. doi: 10.1016/j.cmet.2018.07.005. Epub 2018 Aug 16. Cell Metab. 2018. PMID: 30122553 Free PMC article.

2

Tumor suppression by p53: fall of the triumvirate?

Hock AK, Vousden KH. Hock AK, et al. Cell. 2012 Jun 8;149(6):1183-5. doi: 10.1016/j.cell.2012.05.024. Cell. 2012. PMID: 22682240 Free article.

3

The role of ubiquitin modification in the regulation of p53.

Hock AK, Vousden KH. Hock AK, et al. Biochim Biophys Acta. 2014 Jan;1843(1):137-49. doi: 10.1016/j.bbamcr.2013.05.022. Epub 2013 Jun 3. Biochim Biophys Acta. 2014. PMID: 23742843 Free article. Review.

4

p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant.

Humpton TJ, Hock AK, Maddocks ODK, Vousden KH. Humpton TJ, et al. Among authors: hock ak. Cancer Metab. 2018 Dec 3;6:18. doi: 10.1186/s40170-018-0191-6. eCollection 2018. Cancer Metab. 2018. PMID: 30524726 Free PMC article.

5

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.

Blagih J, Zani F, Chakravarty P, Hennequart M, Pilley S, Hobor S, Hock AK, Walton JB, Morton JP, Gronroos E, Mason S, Yang M, McNeish I, Swanton C, Blyth K, Vousden KH. Blagih J, et al. Among authors: hock ak. Cell Rep. 2020 Jan 14;30(2):481-496.e6. doi: 10.1016/j.celrep.2019.12.028. Cell Rep. 2020. PMID: 31940491 Free PMC article.

6

Regulation of the p53 pathway by ubiquitin and related proteins.

Hock A, Vousden KH. Hock A, et al. Int J Biochem Cell Biol. 2010 Oct;42(10):1618-21. doi: 10.1016/j.biocel.2010.06.011. Epub 2010 Jun 17. Int J Biochem Cell Biol. 2010. PMID: 20601087 Review.

7

p53- and p73-independent activation of TIGAR expression in vivo.

Lee P, Hock AK, Vousden KH, Cheung EC. Lee P, et al. Among authors: hock ak. Cell Death Dis. 2015 Aug 6;6(8):e1842. doi: 10.1038/cddis.2015.205. Cell Death Dis. 2015. PMID: 26247727 Free PMC article.

8

Regulation of p53 stability and function by the deubiquitinating enzyme USP42.

Hock AK, Vigneron AM, Carter S, Ludwig RL, Vousden KH. Hock AK, et al. EMBO J. 2011 Nov 15;30(24):4921-30. doi: 10.1038/emboj.2011.419. EMBO J. 2011. PMID: 22085928 Free PMC article.

9

Small molecules that bind the Mdm2 RING stabilize and activate p53.

Roxburgh P, Hock AK, Dickens MP, Mezna M, Fischer PM, Vousden KH. Roxburgh P, et al. Among authors: hock ak. Carcinogenesis. 2012 Apr;33(4):791-8. doi: 10.1093/carcin/bgs092. Epub 2012 Feb 2. Carcinogenesis. 2012. PMID: 22301280

10

Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.

Nomura K, Klejnot M, Kowalczyk D, Hock AK, Sibbet GJ, Vousden KH, Huang DT. Nomura K, et al. Among authors: hock ak. Nat Struct Mol Biol. 2017 Jul;24(7):578-587. doi: 10.1038/nsmb.3414. Epub 2017 May 29. Nat Struct Mol Biol. 2017. PMID: 28553961 Free PMC article.

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