Castrillon DH - Search Results

1

Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load.

Li HD, Cuevas I, Zhang M, Lu C, Alam MM, Fu YX, You MJ, Akbay EA, Zhang H, Castrillon DH. Li HD, et al. Among authors: castrillon dh. J Clin Invest. 2018 Aug 31;128(9):4179-4191. doi: 10.1172/JCI122095. Epub 2018 Aug 20. J Clin Invest. 2018. PMID: 30124468 Free PMC article.

2

A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response.

Li HD, Lu C, Zhang H, Hu Q, Zhang J, Cuevas IC, Sahoo SS, Aguilar M, Maurais EG, Zhang S, Wang X, Akbay EA, Li GM, Li B, Koduru P, Ly P, Fu YX, Castrillon DH. Li HD, et al. Among authors: castrillon dh. JCI Insight. 2020 Jul 23;5(14):e138829. doi: 10.1172/jci.insight.138829. JCI Insight. 2020. PMID: 32699191 Free PMC article.

3

FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity.

Sahoo SS, Ramanand SG, Gao Y, Abbas A, Kumar A, Cuevas IC, Li HD, Aguilar M, Xing C, Mani RS, Castrillon DH. Sahoo SS, et al. Among authors: castrillon dh. J Clin Invest. 2022 Jun 15;132(12):e157574. doi: 10.1172/JCI157574. J Clin Invest. 2022. PMID: 35703180 Free PMC article.

4

Serial genomic analysis of endometrium supports the existence of histologically indistinct endometrial cancer precursors.

Aguilar M, Zhang H, Zhang M, Cantarell B, Sahoo SS, Li HD, Cuevas IC, Lea J, Miller DS, Chen H, Zheng W, Gagan J, Lucas E, Castrillon DH. Aguilar M, et al. Among authors: castrillon dh. J Pathol. 2021 May;254(1):20-30. doi: 10.1002/path.5628. Epub 2021 Mar 9. J Pathol. 2021. PMID: 33506979 Free PMC article.

5

The mismatch recognition protein MutSα promotes nascent strand degradation at stalled replication forks.

Zhang J, Zhao X, Liu L, Li HD, Gu L, Castrillon DH, Li GM. Zhang J, et al. Among authors: castrillon dh. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2201738119. doi: 10.1073/pnas.2201738119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161943 Free PMC article.

6

Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy.

Contreras CM, Akbay EA, Gallardo TD, Haynie JM, Sharma S, Tagao O, Bardeesy N, Takahashi M, Settleman J, Wong KK, Castrillon DH. Contreras CM, et al. Among authors: castrillon dh. Dis Model Mech. 2010 Mar-Apr;3(3-4):181-93. doi: 10.1242/dmm.004440. Epub 2010 Feb 8. Dis Model Mech. 2010. PMID: 20142330 Free PMC article.

7

Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis.

Akbay EA, Peña CG, Ruder D, Michel JA, Nakada Y, Pathak S, Multani AS, Chang S, Castrillon DH. Akbay EA, et al. Among authors: castrillon dh. Oncogene. 2013 Apr 25;32(17):2211-9. doi: 10.1038/onc.2012.232. Epub 2012 Jun 11. Oncogene. 2013. PMID: 22689059 Free PMC article.

8

Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas.

Contreras CM, Gurumurthy S, Haynie JM, Shirley LJ, Akbay EA, Wingo SN, Schorge JO, Broaddus RR, Wong KK, Bardeesy N, Castrillon DH. Contreras CM, et al. Among authors: castrillon dh. Cancer Res. 2008 Feb 1;68(3):759-66. doi: 10.1158/0008-5472.CAN-07-5014. Cancer Res. 2008. PMID: 18245476

9

Somatic LKB1 mutations promote cervical cancer progression.

Wingo SN, Gallardo TD, Akbay EA, Liang MC, Contreras CM, Boren T, Shimamura T, Miller DS, Sharpless NE, Bardeesy N, Kwiatkowski DJ, Schorge JO, Wong KK, Castrillon DH. Wingo SN, et al. Among authors: castrillon dh. PLoS One. 2009;4(4):e5137. doi: 10.1371/journal.pone.0005137. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340305 Free PMC article.

10

Control of Oocyte Reawakening by Kit.

Saatcioglu HD, Cuevas I, Castrillon DH. Saatcioglu HD, et al. Among authors: castrillon dh. PLoS Genet. 2016 Aug 8;12(8):e1006215. doi: 10.1371/journal.pgen.1006215. eCollection 2016 Aug. PLoS Genet. 2016. PMID: 27500836 Free PMC article.

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