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Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis.
Zakaria C, Sean P, Hoang HD, Leroux LP, Watson M, Workenhe ST, Hearnden J, Pearl D, Truong VT, Robichaud N, Yanagiya A, Tahmasebi S, Jafarnejad SM, Jia JJ, Pelin A, Diallo JS, Le Boeuf F, Bell JC, Mossman KL, Graber TE, Jaramillo M, Sonenberg N, Alain T. Zakaria C, et al. Among authors: hoang hd. PLoS Pathog. 2018 Aug 23;14(8):e1007264. doi: 10.1371/journal.ppat.1007264. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30138450 Free PMC article.
La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).
Fonseca BD, Zakaria C, Jia JJ, Graber TE, Svitkin Y, Tahmasebi S, Healy D, Hoang HD, Jensen JM, Diao IT, Lussier A, Dajadian C, Padmanabhan N, Wang W, Matta-Camacho E, Hearnden J, Smith EM, Tsukumo Y, Yanagiya A, Morita M, Petroulakis E, González JL, Hernández G, Alain T, Damgaard CK. Fonseca BD, et al. Among authors: hoang hd. J Biol Chem. 2015 Jun 26;290(26):15996-6020. doi: 10.1074/jbc.M114.621730. Epub 2015 May 4. J Biol Chem. 2015. PMID: 25940091 Free PMC article.
S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.
Wang F, Alain T, Szretter KJ, Stephenson K, Pol JG, Atherton MJ, Hoang HD, Fonseca BD, Zakaria C, Chen L, Rangwala Z, Hesch A, Chan ESY, Tuinman C, Suthar MS, Jiang Z, Ashkar AA, Thomas G, Kozma SC, Gale M Jr, Fitzgerald KA, Diamond MS, Mossman K, Sonenberg N, Wan Y, Lichty BD. Wang F, et al. Among authors: hoang hd. Nat Immunol. 2016 May;17(5):514-522. doi: 10.1038/ni.3433. Epub 2016 Apr 4. Nat Immunol. 2016. PMID: 27043414 Free PMC article.
UPF1 Governs Synaptic Plasticity through Association with a STAU2 RNA Granule.
Graber TE, Freemantle E, Anadolu MN, Hébert-Seropian S, MacAdam RL, Shin U, Hoang HD, Alain T, Lacaille JC, Sossin WS. Graber TE, et al. Among authors: hoang hd. J Neurosci. 2017 Sep 20;37(38):9116-9131. doi: 10.1523/JNEUROSCI.0088-17.2017. Epub 2017 Aug 18. J Neurosci. 2017. PMID: 28821679 Free PMC article.
CARMAL Is a Long Non-coding RNA Locus That Regulates MFGE8 Expression.
Soubeyrand S, Nikpay M, Lau P, Turner A, Hoang HD, Alain T, McPherson R. Soubeyrand S, et al. Among authors: hoang hd. Front Genet. 2020 Jun 17;11:631. doi: 10.3389/fgene.2020.00631. eCollection 2020. Front Genet. 2020. PMID: 32625236 Free PMC article.
Emerging translation strategies during virus-host interaction.
Hoang HD, Neault S, Pelin A, Alain T. Hoang HD, et al. Wiley Interdiscip Rev RNA. 2021 Jan;12(1):e1619. doi: 10.1002/wrna.1619. Epub 2020 Aug 5. Wiley Interdiscip Rev RNA. 2021. PMID: 32757266 Free PMC article. Review.
mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1.
Jia JJ, Lahr RM, Solgaard MT, Moraes BJ, Pointet R, Yang AD, Celucci G, Graber TE, Hoang HD, Niklaus MR, Pena IA, Hollensen AK, Smith EM, Chaker-Margot M, Anton L, Dajadian C, Livingstone M, Hearnden J, Wang XD, Yu Y, Maier T, Damgaard CK, Berman AJ, Alain T, Fonseca BD. Jia JJ, et al. Among authors: hoang hd. Nucleic Acids Res. 2021 Apr 6;49(6):3461-3489. doi: 10.1093/nar/gkaa1239. Nucleic Acids Res. 2021. PMID: 33398329 Free PMC article.
Near real-time determination of B.1.1.7 in proportion to total SARS-CoV-2 viral load in wastewater using an allele-specific primer extension PCR strategy.
Graber TE, Mercier É, Bhatnagar K, Fuzzen M, D'Aoust PM, Hoang HD, Tian X, Towhid ST, Plaza-Diaz J, Eid W, Alain T, Butler A, Goodridge L, Servos M, Delatolla R. Graber TE, et al. Among authors: hoang hd. Water Res. 2021 Oct 15;205:117681. doi: 10.1016/j.watres.2021.117681. Epub 2021 Sep 23. Water Res. 2021. PMID: 34619611 Free PMC article.
58 results