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Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis.
Zakaria C, Sean P, Hoang HD, Leroux LP, Watson M, Workenhe ST, Hearnden J, Pearl D, Truong VT, Robichaud N, Yanagiya A, Tahmasebi S, Jafarnejad SM, Jia JJ, Pelin A, Diallo JS, Le Boeuf F, Bell JC, Mossman KL, Graber TE, Jaramillo M, Sonenberg N, Alain T. Zakaria C, et al. Among authors: leroux lp. PLoS Pathog. 2018 Aug 23;14(8):e1007264. doi: 10.1371/journal.ppat.1007264. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30138450 Free PMC article.
Cap-dependent translation initiation monitored in living cells.
Gandin V, English BP, Freeman M, Leroux LP, Preibisch S, Walpita D, Jaramillo M, Singer RH. Gandin V, et al. Among authors: leroux lp. Nat Commun. 2022 Nov 2;13(1):6558. doi: 10.1038/s41467-022-34052-8. Nat Commun. 2022. PMID: 36323665 Free PMC article.
Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts.
Chaparro V, Leroux LP, Masvidal L, Lorent J, Graber TE, Zimmermann A, Arango Duque G, Descoteaux A, Alain T, Larsson O, Jaramillo M. Chaparro V, et al. Among authors: leroux lp. PLoS Pathog. 2020 Jun 1;16(6):e1008291. doi: 10.1371/journal.ppat.1008291. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32479529 Free PMC article.
18 results