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The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma.
Oncotarget. 2018 Jul 31;9(59):31397-31410. doi: 10.18632/oncotarget.25829. eCollection 2018 Jul 31.
Oncotarget. 2018.
PMID: 30140378
Free PMC article.
An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis.
García-Domínguez DJ, Hontecillas-Prieto L, León EA, Sánchez-Molina S, Rodríguez-Núñez P, Morón FJ, Hajji N, Mackintosh C, de Álava E.
García-Domínguez DJ, et al. Among authors: rodriguez nunez p.
PLoS One. 2020 Jun 5;15(6):e0234243. doi: 10.1371/journal.pone.0234243. eCollection 2020.
PLoS One. 2020.
PMID: 32502203
Free PMC article.
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Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma.
Rodríguez-Núñez P, Romero-Pérez L, Amaral AT, Puerto-Camacho P, Jordán C, Marcilla D, Grünewald TG, Alonso J, de Alava E, Díaz-Martín J.
Rodríguez-Núñez P, et al.
J Pathol. 2020 Apr;250(4):374-386. doi: 10.1002/path.5379. Epub 2020 Feb 4.
J Pathol. 2020.
PMID: 31880317
Free article.
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Clinical, genetic and pharmacological data support targeting the MEK5/ERK5 module in lung cancer.
Sánchez-Fdez A, Re-Louhau MF, Rodríguez-Núñez P, Ludeña D, Matilla-Almazán S, Pandiella A, Esparís-Ogando A.
Sánchez-Fdez A, et al. Among authors: rodriguez nunez p.
NPJ Precis Oncol. 2021 Aug 17;5(1):78. doi: 10.1038/s41698-021-00218-8.
NPJ Precis Oncol. 2021.
PMID: 34404896
Free PMC article.
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