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Page 1
Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.
Sollberger G, Choidas A, Burn GL, Habenberger P, Di Lucrezia R, Kordes S, Menninger S, Eickhoff J, Nussbaumer P, Klebl B, Krüger R, Herzig A, Zychlinsky A. Sollberger G, et al. Among authors: kordes s. Sci Immunol. 2018 Aug 24;3(26):eaar6689. doi: 10.1126/sciimmunol.aar6689. Sci Immunol. 2018. PMID: 30143555
Discovery of a Novel Inhibitor of the Hedgehog Signaling Pathway through Cell-based Compound Discovery and Target Prediction.
Kremer L, Schultz-Fademrecht C, Baumann M, Habenberger P, Choidas A, Klebl B, Kordes S, Schöler HR, Sterneckert J, Ziegler S, Schneider G, Waldmann H. Kremer L, et al. Among authors: kordes s. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13021-13025. doi: 10.1002/anie.201707394. Epub 2017 Sep 18. Angew Chem Int Ed Engl. 2017. PMID: 28833911
Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo.
Reinhardt L, Kordes S, Reinhardt P, Glatza M, Baumann M, Drexler HCA, Menninger S, Zischinsky G, Eickhoff J, Fröb C, Bhattarai P, Arulmozhivarman G, Marrone L, Janosch A, Adachi K, Stehling M, Anderson EN, Abo-Rady M, Bickle M, Pandey UB, Reimer MM, Kizil C, Schöler HR, Nussbaumer P, Klebl B, Sterneckert JL. Reinhardt L, et al. Among authors: kordes s. Stem Cell Reports. 2019 Mar 5;12(3):502-517. doi: 10.1016/j.stemcr.2019.01.015. Epub 2019 Feb 14. Stem Cell Reports. 2019. PMID: 30773488 Free PMC article.
Discovery of the Hedgehog Pathway Inhibitor Pipinib that Targets PI4KIIIß.
Kremer L, Hennes E, Brause A, Ursu A, Robke L, Matsubayashi HT, Nihongaki Y, Flegel J, Mejdrová I, Eickhoff J, Baumann M, Nencka R, Janning P, Kordes S, Schöler HR, Sterneckert J, Inoue T, Ziegler S, Waldmann H. Kremer L, et al. Among authors: kordes s. Angew Chem Int Ed Engl. 2019 Nov 11;58(46):16617-16628. doi: 10.1002/anie.201907632. Epub 2019 Oct 4. Angew Chem Int Ed Engl. 2019. PMID: 31454140 Free PMC article. Review.
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach.
Romero-Romero S, Costas M, Silva Manzano DA, Kordes S, Rojas-Ortega E, Tapia C, Guerra Y, Shanmugaratnam S, Rodríguez-Romero A, Baker D, Höcker B, Fernández-Velasco DA. Romero-Romero S, et al. Among authors: kordes s. J Mol Biol. 2021 Sep 3;433(18):167153. doi: 10.1016/j.jmb.2021.167153. Epub 2021 Jul 14. J Mol Biol. 2021. PMID: 34271011 Free PMC article.
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