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Page 1
Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin.
Panaretakis T, Hjortsberg L, Tamm KP, Björklund AC, Joseph B, Grandér D. Panaretakis T, et al. Among authors: tamm kp. Mol Biol Cell. 2008 Jan;19(1):41-50. doi: 10.1091/mbc.e07-04-0358. Epub 2007 Oct 17. Mol Biol Cell. 2008. PMID: 17942603 Free PMC article.
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy.
Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J, Corcoran M, Björklund AC, Hultenby K, Lundin J, Heyman M, Söderhäll S, Mazur J, Porwit A, Pandolfi PP, Zhivotovsky B, Panaretakis T, Grandér D. Laane E, et al. Among authors: tamm kp. Cell Death Differ. 2009 Jul;16(7):1018-29. doi: 10.1038/cdd.2009.46. Epub 2009 Apr 24. Cell Death Differ. 2009. PMID: 19390558
Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells.
Buentke E, Nordström A, Lin H, Björklund AC, Laane E, Harada M, Lu L, Tegnebratt T, Stone-Elander S, Heyman M, Söderhäll S, Porwit A, Ostenson CG, Shoshan M, Tamm KP, Grandér D. Buentke E, et al. Among authors: tamm kp. Blood Cancer J. 2011 Jul;1(7):e31. doi: 10.1038/bcj.2011.27. Epub 2011 Jul 29. Blood Cancer J. 2011. PMID: 22829187 Free PMC article.
Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies.
Daneshmanesh AH, Porwit A, Hojjat-Farsangi M, Jeddi-Tehrani M, Tamm KP, Grandér D, Lehmann S, Norin S, Shokri F, Rabbani H, Mellstedt H, Österborg A. Daneshmanesh AH, et al. Among authors: tamm kp. Leuk Lymphoma. 2013 Apr;54(4):843-50. doi: 10.3109/10428194.2012.731599. Epub 2012 Oct 9. Leuk Lymphoma. 2013. PMID: 22988987
Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs.
Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey-Bates EG, Edsbäcker E, Pellegrini P, Rassoolzadeh H, Brnjic S, Larsson R, Stark GR, Grandér D, Linder S, Tamm KP, De Milito A. Kolosenko I, et al. Among authors: tamm kp. Int J Cancer. 2015 Feb 15;136(4):E51-61. doi: 10.1002/ijc.29161. Epub 2014 Sep 4. Int J Cancer. 2015. PMID: 25156627
Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies.
Herold N, Rudd SG, Ljungblad L, Sanjiv K, Myrberg IH, Paulin CB, Heshmati Y, Hagenkort A, Kutzner J, Page BD, Calderón-Montaño JM, Loseva O, Jemth AS, Bulli L, Axelsson H, Tesi B, Valerie NC, Höglund A, Bladh J, Wiita E, Sundin M, Uhlin M, Rassidakis G, Heyman M, Tamm KP, Warpman-Berglund U, Walfridsson J, Lehmann S, Grandér D, Lundbäck T, Kogner P, Henter JI, Helleday T, Schaller T. Herold N, et al. Among authors: tamm kp. Nat Med. 2017 Feb;23(2):256-263. doi: 10.1038/nm.4265. Epub 2017 Jan 9. Nat Med. 2017. PMID: 28067901
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