Hildyard JCW - Search Results

1

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy.

Amoasii L, Hildyard JCW, Li H, Sanchez-Ortiz E, Mireault A, Caballero D, Harron R, Stathopoulou TR, Massey C, Shelton JM, Bassel-Duby R, Piercy RJ, Olson EN. Amoasii L, et al. Among authors: hildyard jcw. Science. 2018 Oct 5;362(6410):86-91. doi: 10.1126/science.aau1549. Epub 2018 Aug 30. Science. 2018. PMID: 30166439 Free PMC article.

2

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.

Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. Godfrey C, et al. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155. Epub 2015 May 1. Hum Mol Genet. 2015. PMID: 25935000 Free PMC article.

3

Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy.

Hildyard JC, Wells DJ. Hildyard JC, et al. PLoS Curr. 2016 Jun 16;8:ecurrents.md.99d88e72634387639707601b237467d7. doi: 10.1371/currents.md.99d88e72634387639707601b237467d7. PLoS Curr. 2016. PMID: 27525173 Free PMC article.

4

Determination of qPCR Reference Genes Suitable for Normalizing Gene Expression in a Canine Model of Duchenne Muscular Dystrophy.

Hildyard JCW, Taylor-Brown F, Massey C, Wells DJ, Piercy RJ. Hildyard JCW, et al. J Neuromuscul Dis. 2018;5(2):177-191. doi: 10.3233/JND-170267. J Neuromuscul Dis. 2018. PMID: 29614692

5

Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy.

Hildyard JCW, Finch AM, Wells DJ. Hildyard JCW, et al. PLoS One. 2019 Jan 30;14(1):e0211384. doi: 10.1371/journal.pone.0211384. eCollection 2019. PLoS One. 2019. PMID: 30699165 Free PMC article.

6

Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo.

Hildyard JCW, Crawford AH, Rawson F, Riddell DO, Harron RCM, Piercy RJ. Hildyard JCW, et al. Wellcome Open Res. 2020 Jul 20;5:76. doi: 10.12688/wellcomeopenres.15762.2. eCollection 2020. Wellcome Open Res. 2020. PMID: 32724863 Free PMC article.

7

Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics.

Hildyard JCW, Rawson F, Wells DJ, Piercy RJ. Hildyard JCW, et al. PLoS One. 2020 Sep 24;15(9):e0239467. doi: 10.1371/journal.pone.0239467. eCollection 2020. PLoS One. 2020. PMID: 32970731 Free PMC article.

8

Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy.

Verhaart IEC, Cappellari O, Tanganyika-de Winter CL, Plomp JJ, Nnorom S, Wells KE, Hildyard JCW, Bull D, Aartsma-Rus A, Wells DJ. Verhaart IEC, et al. Among authors: hildyard jcw. J Neuromuscul Dis. 2021;8(5):845-863. doi: 10.3233/JND-200524. J Neuromuscul Dis. 2021. PMID: 33044191 Free PMC article.

9

Validation of DE50-MD dogs as a model for the brain phenotype of Duchenne muscular dystrophy.

Crawford AH, Hildyard JCW, Rushing SAM, Wells DJ, Diez-Leon M, Piercy RJ. Crawford AH, et al. Among authors: hildyard jcw. Dis Model Mech. 2022 Mar 1;15(3):dmm049291. doi: 10.1242/dmm.049291. Epub 2022 Mar 2. Dis Model Mech. 2022. PMID: 35019137 Free PMC article.

10

Identification of qPCR reference genes suitable for normalising gene expression in the developing mouse embryo.

Hildyard JCW, Wells DJ, Piercy RJ. Hildyard JCW, et al. Wellcome Open Res. 2022 Sep 21;6:197. doi: 10.12688/wellcomeopenres.16972.2. eCollection 2021. Wellcome Open Res. 2022. PMID: 35509373 Free PMC article.

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