Popplewell L - Search Results

1

Antisense Oligonucleotide Targeting of 3'-UTR of mRNA for Expression Knockdown.

Golshirazi G, Ciszewski L, Lu-Nguyen N, Popplewell L. Golshirazi G, et al. Among authors: popplewell l. Methods Mol Biol. 2018;1828:91-124. doi: 10.1007/978-1-4939-8651-4_6. Methods Mol Biol. 2018. PMID: 30171537

2

Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials.

Popplewell LJ, Adkin C, Arechavala-Gomeza V, Aartsma-Rus A, de Winter CL, Wilton SD, Morgan JE, Muntoni F, Graham IR, Dickson G. Popplewell LJ, et al. Neuromuscul Disord. 2010 Feb;20(2):102-10. doi: 10.1016/j.nmd.2009.10.013. Epub 2010 Jan 15. Neuromuscul Disord. 2010. PMID: 20079639

3

Bioinformatic and functional optimization of antisense phosphorodiamidate morpholino oligomers (PMOs) for therapeutic modulation of RNA splicing in muscle.

Popplewell LJ, Graham IR, Malerba A, Dickson G. Popplewell LJ, et al. Methods Mol Biol. 2011;709:153-78. doi: 10.1007/978-1-61737-982-6_10. Methods Mol Biol. 2011. PMID: 21194027

4

Optimizing antisense oligonucleotides using phosphorodiamidate morpholino oligomers.

Popplewell LJ, Malerba A, Dickson G. Popplewell LJ, et al. Methods Mol Biol. 2012;867:143-67. doi: 10.1007/978-1-61779-767-5_10. Methods Mol Biol. 2012. PMID: 22454060

5

Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice.

Lu-Nguyen NB, Jarmin SA, Saleh AF, Popplewell L, Gait MJ, Dickson G. Lu-Nguyen NB, et al. Among authors: popplewell l. Mol Ther. 2015 Aug;23(8):1341-1348. doi: 10.1038/mt.2015.88. Epub 2015 May 11. Mol Ther. 2015. PMID: 25959011 Free PMC article.

6

Antisense targeting of 3' end elements involved in DUX4 mRNA processing is an efficient therapeutic strategy for facioscapulohumeral dystrophy: a new gene-silencing approach.

Marsollier AC, Ciszewski L, Mariot V, Popplewell L, Voit T, Dickson G, Dumonceaux J. Marsollier AC, et al. Among authors: popplewell l. Hum Mol Genet. 2016 Apr 15;25(8):1468-78. doi: 10.1093/hmg/ddw015. Epub 2016 Jan 19. Hum Mol Genet. 2016. PMID: 26787513

7

Systemic Antisense Therapeutics for Dystrophin and Myostatin Exon Splice Modulation Improve Muscle Pathology of Adult mdx Mice.

Lu-Nguyen N, Malerba A, Popplewell L, Schnell F, Hanson G, Dickson G. Lu-Nguyen N, et al. Among authors: popplewell l. Mol Ther Nucleic Acids. 2017 Mar 17;6:15-28. doi: 10.1016/j.omtn.2016.11.009. Epub 2016 Dec 10. Mol Ther Nucleic Acids. 2017. PMID: 28325281 Free PMC article.

8

Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9.

Koo T, Lu-Nguyen NB, Malerba A, Kim E, Kim D, Cappellari O, Cho HY, Dickson G, Popplewell L, Kim JS. Koo T, et al. Among authors: popplewell l. Mol Ther. 2018 Jun 6;26(6):1529-1538. doi: 10.1016/j.ymthe.2018.03.018. Epub 2018 Mar 30. Mol Ther. 2018. PMID: 29730196 Free PMC article.

9

Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides.

March JT, Golshirazi G, Cernisova V, Carr H, Leong Y, Lu-Nguyen N, Popplewell LJ. March JT, et al. Biomedicines. 2018 Jun 25;6(3):74. doi: 10.3390/biomedicines6030074. Biomedicines. 2018. PMID: 29941814 Free PMC article. Review.

10

A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures.

Hiller M, Falzarano MS, Garcia-Jimenez I, Sardone V, Verheul RC, Popplewell L, Anthony K, Ruiz-Del-Yerro E, Osman H, Goeman JJ, Mamchaoui K, Dickson G, Ferlini A, Muntoni F, Aartsma-Rus A, Arechavala-Gomeza V, Datson NA, Spitali P. Hiller M, et al. Among authors: popplewell l. PLoS One. 2018 Oct 2;13(10):e0204485. doi: 10.1371/journal.pone.0204485. eCollection 2018. PLoS One. 2018. PMID: 30278058 Free PMC article.

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