Girreser U - Search Results

1

Axitinib: A Photoswitchable Approved Tyrosine Kinase Inhibitor.

Schmidt D, Rodat T, Heintze L, Weber J, Horbert R, Girreser U, Raeker T, Bußmann L, Kriegs M, Hartke B, Peifer C. Schmidt D, et al. Among authors: girreser u. ChemMedChem. 2018 Nov 20;13(22):2415-2426. doi: 10.1002/cmdc.201800531. Epub 2018 Nov 5. ChemMedChem. 2018. PMID: 30199151

2

A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment.

Meier C, Steinhauer TN, Koczian F, Plitzko B, Jarolim K, Girreser U, Braig S, Marko D, Vollmar AM, Clement B. Meier C, et al. Among authors: girreser u. ChemMedChem. 2017 Mar 7;12(5):347-352. doi: 10.1002/cmdc.201700026. Epub 2017 Feb 8. ChemMedChem. 2017. PMID: 28099785

3

11-Substituted Benzo[c]phenanthridines: New Structures and Insight into Their Mode of Antiproliferative Action.

Clement B, Girreser U, Steinhauer TN, Meier C, Marko D, Aichinger G, Kaltefleiter I, Stenzel L, Heber D, Weide M, Wolschendorf U, Zebothsen I, Zur Nieden D. Clement B, et al. Among authors: girreser u. ChemMedChem. 2016 Oct 6;11(19):2155-2170. doi: 10.1002/cmdc.201600199. Epub 2016 Aug 22. ChemMedChem. 2016. PMID: 27546098

4

Electrochemical and mARC-catalyzed enzymatic reduction of para-substituted benzamidoximes: consequences for the prodrug concept "amidoximes instead of amidines".

Bauch E, Reichmann D, Mendel RR, Bittner F, Manke AM, Kurz P, Girreser U, Havemeyer A, Clement B. Bauch E, et al. Among authors: girreser u. ChemMedChem. 2015 Feb;10(2):360-7. doi: 10.1002/cmdc.201402437. Epub 2014 Dec 15. ChemMedChem. 2015. PMID: 25512261

5

Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.

Bluhm U, Boucher JL, Buss U, Clement B, Friedrich F, Girreser U, Heber D, Lam T, Lepoivre M, Rostaie-Gerylow M, Wolschendorf U. Bluhm U, et al. Among authors: girreser u. Eur J Med Chem. 2009 Jul;44(7):2877-87. doi: 10.1016/j.ejmech.2008.12.007. Epub 2008 Dec 16. Eur J Med Chem. 2009. PMID: 19144449

6

Design, Synthesis, and Bioactivation of O-Glycosylated Prodrugs of the Natural Nitric Oxide Precursor N(ω)-Hydroxy-l-arginine.

Litty FA, Gudd J, Girreser U, Clement B, Schade D. Litty FA, et al. Among authors: girreser u. J Med Chem. 2016 Sep 8;59(17):8030-41. doi: 10.1021/acs.jmedchem.6b00810. Epub 2016 Aug 29. J Med Chem. 2016. PMID: 27548300

7

Detoxification of Trimethylamine N-Oxide by the Mitochondrial Amidoxime Reducing Component mARC.

Schneider J, Girreser U, Havemeyer A, Bittner F, Clement B. Schneider J, et al. Among authors: girreser u. Chem Res Toxicol. 2018 Jun 18;31(6):447-453. doi: 10.1021/acs.chemrestox.7b00329. Epub 2018 Jun 1. Chem Res Toxicol. 2018. PMID: 29856598

8

Metabolism of N-hydroxyguanidines (N-hydroxydebrisoquine) in human and porcine hepatocytes: reduction and formation of glucuronides.

Froehlich AK, Girreser U, Clement B. Froehlich AK, et al. Among authors: girreser u. Drug Metab Dispos. 2005 Oct;33(10):1532-7. doi: 10.1124/dmd.105.004572. Epub 2005 Jul 20. Drug Metab Dispos. 2005. PMID: 16033947

9

Oxygen-insensitive enzymatic reduction of oximes to imines.

Heberling S, Girreser U, Wolf S, Clement B. Heberling S, et al. Among authors: girreser u. Biochem Pharmacol. 2006 Jan 12;71(3):354-65. doi: 10.1016/j.bcp.2005.10.037. Biochem Pharmacol. 2006. PMID: 16324684

10

Phase 2 metabolites of N-hydroxylated amidines (amidoximes): synthesis, in vitro formation by pig hepatocytes, and mutagenicity testing.

Clement B, Christiansen K, Girreser U. Clement B, et al. Among authors: girreser u. Chem Res Toxicol. 2001 Mar;14(3):319-26. doi: 10.1021/tx000105f. Chem Res Toxicol. 2001. PMID: 11258982

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